Type IV collagen reduces mucin 5AC secretion in three-dimensional cultured human primary airway epithelial cells
Sign Up to like & getrecommendations! Published in 2019 at "Biochemistry and Biophysics Reports"
DOI: 10.1016/j.bbrep.2019.100707
Abstract: Mucin 5AC (MUC5AC) hypersecretion induces airway narrowing in patients with asthma, which leads to breathing problems. We investigated the regulation of MUC5AC secretion by extracellular matrix (ECM) proteins in human primary airway epithelial cells from… read more here.
Keywords: muc5ac secretion; secretion; primary airway; human primary ... See more keywords
In primary airway epithelial cells, the unjamming transition is distinct from the epithelial-to-mesenchymal transition
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-18841-7
Abstract: The epithelial-to-mesenchymal transition (EMT) and the unjamming transition (UJT) each comprises a gateway to cellular migration, plasticity and remodeling, but the extent to which these core programs are distinct, overlapping, or identical has remained undefined.… read more here.
Keywords: epithelial cells; mesenchymal transition; unjamming transition; transition ... See more keywords
Nebulized Menthol Impairs Mucociliary Clearance via TRPM8 and MUC5AC/MUC5B in Primary Airway Epithelial Cells
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24021694
Abstract: Flavorings enhance the palatability of e-cigarettes (e-cigs), with menthol remaining a popular choice among e-cig users. Menthol flavor remains one of the only flavors approved by the United States FDA for use in commercially available,… read more here.
Keywords: menthol; airway epithelial; nebulized menthol; primary airway ... See more keywords