Use of Steroid Profiling Combined With Machine Learning for Identification and Subtype Classification in Primary Aldosteronism
Sign Up to like & getrecommendations! Published in 2020 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2020.16209
Abstract: Key Points Question Does steroid profiling combined with machine learning offer a potential 1-step strategy to facilitate diagnosis and subtype classification for treatment stratification of patients with primary aldosteronism? Findings This diagnostic study involving patients… read more here.
Keywords: steroid profiling; aldosteronism; machine learning; profiling combined ... See more keywords
Refining the Definitions of Biochemical and Clinical Cure for Primary Aldosteronism Using the Primary Aldosteronism Surgical Outcome (PASO) Classification System
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DOI: 10.1007/s00268-017-4311-1
Abstract: IntroductionDetermination of outcomes after adrenalectomy for primary aldosteronism (PA) is limited by the lack of standardized definitions of cure. The Primary Aldosteronism Surgical Outcomes (PASO) group recently established new consensus definitions for biochemical and clinical… read more here.
Keywords: aldosteronism; primary aldosteronism; paso; biochemical clinical ... See more keywords
Adrenalectomy for Primary Aldosteronism: Significant Variability in Work-Up Strategies and Low Guideline Adherence in Worldwide Daily Clinical Practice
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DOI: 10.1007/s00268-020-05408-2
Abstract: Background Various diagnostic tests are available to establish the primary aldosteronism (PA) diagnosis and to determine the disease laterality. Combined with the controversies in the literature, unawareness of guidelines and technical demands and high costs… read more here.
Keywords: work; primary aldosteronism; clinical practice; daily clinical ... See more keywords
Associations of aldosterone and renin concentrations with inflammation—the Study of Health in Pomerania and the German Conn’s Registry
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DOI: 10.1007/s12020-017-1348-8
Abstract: PurposeChronic inflammation is an age-independent and body mass index-independent contributor to the development of multi-morbidity. Alterations of the renin-angiotensin-aldosterone system are observed within the context of proinflammatory states. We assessed circulating aldosterone, renin, and inflammatory… read more here.
Keywords: plasma; primary aldosteronism; renin; study health ... See more keywords
11C-metomidate PET in the diagnosis of adrenal masses and primary aldosteronism: a review of the literature
Sign Up to like & getrecommendations! Published in 2020 at "Endocrine"
DOI: 10.1007/s12020-020-02474-3
Abstract: Adrenal masses are commonly encountered in clinical practice, many of whom are incidental. Identifying malignancy, and excess hormone production is essential for appropriate management. Biochemical workup and imaging tests (dedicated adrenal CT and/or MRI) are… read more here.
Keywords: 11c metomidate; primary aldosteronism; adrenal masses; review ... See more keywords
Development and validation of a novel diagnostic nomogram model to predict primary aldosteronism in patients with hypertension
Sign Up to like & getrecommendations! Published in 2021 at "Endocrine"
DOI: 10.1007/s12020-021-02745-7
Abstract: Primary aldosteronism (PA) remains, to a large extent, an under-diagnosed disease. We aimed to develop and validate a novel clinical nomogram to predict PA based on routine biochemical variables including new ones, calcium-phosphorus product. Records… read more here.
Keywords: patients hypertension; primary aldosteronism; validation; nomogram model ... See more keywords
Screening for primary aldosteronism is underutilised in patients with chronic kidney disease
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Nephrology"
DOI: 10.1007/s40620-022-01267-3
Abstract: Primary aldosteronism (PA) is the most common and potentially curable endocrine cause of secondary hypertension, and carries a worse prognosis than essential hypertension. Despite the high prevalence of hypertension in patients with chronic kidney disease… read more here.
Keywords: primary aldosteronism; nephrology; aldosteronism; disease ... See more keywords
Surgical treatment outcome of primary aldosteronism assessed using new modified diagnostic tests
Sign Up to like & getrecommendations! Published in 2021 at "Hormones"
DOI: 10.1007/s42000-021-00280-8
Abstract: Primary aldosteronism (PA) is the most frequent type of endocrine hypertension. In our previous studies, we introduced two modified diagnostic tests for PA, the post-dexamethasone saline infusion test (DSIT) and the overnight dexamethasone, captopril, and… read more here.
Keywords: surgical treatment; primary aldosteronism; diagnostic tests; treatment outcome ... See more keywords
Association of aldosterone and blood pressure with the risk for cardiovascular events after treatments in primary aldosteronism.
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DOI: 10.1016/j.atherosclerosis.2021.03.033
Abstract: BACKGROUND AND AIMS We used a dataset from a Japanese nationwide registry of patients with primary aldosteronism, to determine which of the parameters of hyperaldosteronism and blood pressure before or after treatments for primary aldosteronism… read more here.
Keywords: aldosterone renin; treatment; pressure; primary aldosteronism ... See more keywords
Primary Aldosteronism: JACC State-of-the-Art Review.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2019.09.057
Abstract: Primary aldosteronism (PA) is a common, but frequently overlooked, cause of arterial hypertension and excess cardiovascular events, particularly atrial fibrillation. As timely diagnosis and treatment can provide a cure of hyperaldosteronism and hypertension, even when… read more here.
Keywords: aldosteronism; art review; primary aldosteronism; aldosteronism jacc ... See more keywords
Taiwan mini-frontier of primary aldosteronism: Updating detection and diagnosis.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the Formosan Medical Association = Taiwan yi zhi"
DOI: 10.1016/j.jfma.2020.08.001
Abstract: BACKGROUND To update information about the internationally accepted standards and clinical recommendations for the detection and diagnosis of primary aldosteronism (PA). METHODS The Taiwan Society of Aldosteronism (TSA) Task Force reviewed the latest literature and… read more here.
Keywords: detection diagnosis; detection; primary aldosteronism; diagnosis ... See more keywords