Mechanistic Insight into the Catalytic Promiscuity of Amine Dehydrogenases: Asymmetric Synthesis of Secondary and Primary Amines
Sign Up to like & getrecommendations! Published in 2019 at "Chembiochem"
DOI: 10.1002/cbic.201800626
Abstract: Biocatalytic asymmetric amination of ketones, by using amine dehydrogenases (AmDHs) or transaminases, is an efficient method for the synthesis of α‐chiral primary amines. A major challenge is to extend amination to the synthesis of secondary… read more here.
Keywords: primary amines; synthesis secondary; nad dependent; secondary amines ... See more keywords
High performance of nitrogen-doped carbon-supported cobalt catalyst for the mild and selective synthesis of primary amines
Sign Up to like & getrecommendations! Published in 2020 at "Arabian Journal of Chemistry"
DOI: 10.1016/j.arabjc.2020.01.011
Abstract: Abstract A nitrogen-doped carbon-supported Co catalyst (Co/N-C-800) was discovered to be highly active for the reductive amination of carbonyl compounds with NH3 and the hydrogenation of nitriles into primary amines using H2 as the hydrogen… read more here.
Keywords: primary amines; doped carbon; nitrogen doped; carbon supported ... See more keywords
General Dialdehyde Click Chemistry for Amine Bioconjugation.
Sign Up to like & getrecommendations! Published in 2017 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.7b00106
Abstract: The development of methods for conjugating a range of molecules to primary amine functional groups has revolutionized the fields of chemistry, biology, and material science. The primary amine is a key functional group and one… read more here.
Keywords: primary amines; click chemistry; dialdehyde; chemistry ... See more keywords
Reaction of Amino Acids with Ferrate(VI): Impact of the Carboxylic Group on the Primary Amine Oxidation Kinetics and Mechanism.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental science & technology"
DOI: 10.1021/acs.est.2c03319
Abstract: Ferrate (Fe(VI)) is a novel oxidant that can be used to mitigate disinfection byproduct (DBP) precursors. However, the reaction of Fe(VI) with organic nitrogen, which is a potential precursor of potent nitrogenous DBPs, remains largely… read more here.
Keywords: carboxylic group; amino acids; oxidation; primary amine ... See more keywords
A Germanium Catalyst Accelerates the Photoredox α-C(sp3)-H Alkylation of Primary Amines.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c00871
Abstract: Site-selective C(sp3)-H functionalizations using photoredox catalysis (PC) and hydrogen atom transfer (HAT) catalysis have received increasing attention. Here, we report a Ph2GeCl2 cocatalyst that greatly improves the yield of α-C(sp3)-H alkylation of primary amines catalyzed… read more here.
Keywords: catalyst accelerates; germanium catalyst; alkylation primary; sp3 alkylation ... See more keywords
Regio- and Chemoselective Copper-Catalyzed Formal [2+2+2] Cycloaddition of Primary Amines with Arylacetylenes to 2,4,5-Trisubstituted Pyridines.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c02606
Abstract: Disclosed herein is an efficient strategy for the synthesis of 2,4,5-trisubstituted pyridines via CuI/NBS-catalyzed formal intermolecular [2+2+2] cycloaddition of easily available primary amines and nonactivated terminal alkynes. Moreover, this given reaction features a new mode… read more here.
Keywords: catalyzed formal; regio chemoselective; chemoselective copper; trisubstituted pyridines ... See more keywords
Electrochemical Isothiocyanation of Primary Amines.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c00128
Abstract: Isothiocyanates are ubiquitous building blocks used across the fields. Nevertheless, their classical syntheses very often rely on the use of toxic and expensive reagents. Herein, we report a new practical, mild, high-yielding, and supporting-electrolyte-free electrochemical… read more here.
Keywords: primary amines; isothiocyanation primary; electrochemical isothiocyanation;
Ambient-Temperature Synthesis of Primary Amines via Reductive Amination of Carbonyl Compounds
Sign Up to like & getrecommendations! Published in 2020 at "ACS Catalysis"
DOI: 10.1021/acscatal.0c01872
Abstract: Efficient synthesis of primary amines via low-temperature reductive amination of carbonyl compounds using NH3 and H2 as the nitrogen and hydrogen resources is highly desired and challenging in the ... read more here.
Keywords: primary amines; amines via; synthesis primary; carbonyl compounds ... See more keywords
Ru-Catalyzed Hydrogenation–Decarbonylation of Amino Acids to Bio-based Primary Amines
Sign Up to like & getrecommendations! Published in 2017 at "ACS Sustainable Chemistry & Engineering"
DOI: 10.1021/acssuschemeng.6b03140
Abstract: Amino acids are considered to be a valuable renewable resource for the production of bio-based chemicals. Here, the Ru-catalyzed hydrogenation–decarbonylation toward primary amines is presented. In contrast to the direct Pd-catalyzed decarboxylation, this catalytic system… read more here.
Keywords: amino; primary amines; amino acids; catalyzed hydrogenation ... See more keywords
A dual biomimetic process for the selective aerobic oxidative coupling of primary amines using pyrogallol as a precatalyst. Isolation of the [5 + 2] cycloaddition redox intermediates
Sign Up to like & getrecommendations! Published in 2020 at "Green Chemistry"
DOI: 10.1039/c9gc03992a
Abstract: A bioinspired organocatalytic cascade reaction mimicking both purpurogallin biosynthesis and copper amine oxidases (CuAOs) activity is described, at room temperature under ambient air, for the activation of the α-C–H bond of primary amines. The reaction… read more here.
Keywords: cycloaddition redox; primary amines; oxidative coupling; pyrogallol precatalyst ... See more keywords
Mild and selective hydrogenation of nitriles into primary amines over a supported Ni catalyst
Sign Up to like & getrecommendations! Published in 2020 at "New Journal of Chemistry"
DOI: 10.1039/c9nj05307g
Abstract: The development of new heterogeneous non-noble catalytic systems for the selective hydrogenation of nitriles into primary amines is a challenging task. In this study, a mesoporous Al2O3 supported Ni catalyst (denoted as Ni/Al2O3-600, where 600… read more here.
Keywords: primary amines; selective hydrogenation; hydrogenation nitriles; nitriles primary ... See more keywords