Amidophosphine Boranes as Easy Reducing Agents for Efficient Conversion of Nitro Compounds to Primary Amines With Iron Catalyst
Sign Up to like & getrecommendations! Published in 2025 at "Applied Organometallic Chemistry"
DOI: 10.1002/aoc.70015
Abstract: We report a direct and efficient methodology for the hydroboration of aliphatic and aryl nitro compounds using amidophosphine‐borane {(C6H5)CH2N(PPh)2(BH3)2} in the presence of iron(II) chloride as a catalyst under mild conditions to form primary amines… read more here.
Keywords: catalyst; nitro compounds; amidophosphine boranes; iron ... See more keywords
Mechanistic Insight into the Catalytic Promiscuity of Amine Dehydrogenases: Asymmetric Synthesis of Secondary and Primary Amines
Sign Up to like & getrecommendations! Published in 2019 at "Chembiochem"
DOI: 10.1002/cbic.201800626
Abstract: Biocatalytic asymmetric amination of ketones, by using amine dehydrogenases (AmDHs) or transaminases, is an efficient method for the synthesis of α‐chiral primary amines. A major challenge is to extend amination to the synthesis of secondary… read more here.
Keywords: primary amines; synthesis secondary; nad dependent; secondary amines ... See more keywords
High performance of nitrogen-doped carbon-supported cobalt catalyst for the mild and selective synthesis of primary amines
Sign Up to like & getrecommendations! Published in 2020 at "Arabian Journal of Chemistry"
DOI: 10.1016/j.arabjc.2020.01.011
Abstract: Abstract A nitrogen-doped carbon-supported Co catalyst (Co/N-C-800) was discovered to be highly active for the reductive amination of carbonyl compounds with NH3 and the hydrogenation of nitriles into primary amines using H2 as the hydrogen… read more here.
Keywords: primary amines; doped carbon; nitrogen doped; carbon supported ... See more keywords
General Dialdehyde Click Chemistry for Amine Bioconjugation.
Sign Up to like & getrecommendations! Published in 2017 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.7b00106
Abstract: The development of methods for conjugating a range of molecules to primary amine functional groups has revolutionized the fields of chemistry, biology, and material science. The primary amine is a key functional group and one… read more here.
Keywords: primary amines; click chemistry; dialdehyde; chemistry ... See more keywords
Reaction of Amino Acids with Ferrate(VI): Impact of the Carboxylic Group on the Primary Amine Oxidation Kinetics and Mechanism.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental science & technology"
DOI: 10.1021/acs.est.2c03319
Abstract: Ferrate (Fe(VI)) is a novel oxidant that can be used to mitigate disinfection byproduct (DBP) precursors. However, the reaction of Fe(VI) with organic nitrogen, which is a potential precursor of potent nitrogenous DBPs, remains largely… read more here.
Keywords: carboxylic group; amino acids; oxidation; primary amine ... See more keywords
Characterization of Organic Nitrogen by Chlorination, Ozonation, and Stable Isotope Analysis of Nitrate
Sign Up to like & getrecommendations! Published in 2025 at "Environmental Science & Technology"
DOI: 10.1021/acs.est.5c01034
Abstract: During oxidation, nitrogenous species in dissolved organic matter (DOM) are critical in the formation of nitrogenous, potentially toxic disinfection byproducts, but their chemical identity remains poorly understood. Here, we developed three complementary approaches to identify… read more here.
Keywords: peptidic amino; type primary; aryl type; amino acids ... See more keywords
A Germanium Catalyst Accelerates the Photoredox α-C(sp3)-H Alkylation of Primary Amines.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c00871
Abstract: Site-selective C(sp3)-H functionalizations using photoredox catalysis (PC) and hydrogen atom transfer (HAT) catalysis have received increasing attention. Here, we report a Ph2GeCl2 cocatalyst that greatly improves the yield of α-C(sp3)-H alkylation of primary amines catalyzed… read more here.
Keywords: catalyst accelerates; germanium catalyst; alkylation primary; sp3 alkylation ... See more keywords
Regio- and Chemoselective Copper-Catalyzed Formal [2+2+2] Cycloaddition of Primary Amines with Arylacetylenes to 2,4,5-Trisubstituted Pyridines.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c02606
Abstract: Disclosed herein is an efficient strategy for the synthesis of 2,4,5-trisubstituted pyridines via CuI/NBS-catalyzed formal intermolecular [2+2+2] cycloaddition of easily available primary amines and nonactivated terminal alkynes. Moreover, this given reaction features a new mode… read more here.
Keywords: catalyzed formal; regio chemoselective; chemoselective copper; trisubstituted pyridines ... See more keywords
Electrochemical Isothiocyanation of Primary Amines.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c00128
Abstract: Isothiocyanates are ubiquitous building blocks used across the fields. Nevertheless, their classical syntheses very often rely on the use of toxic and expensive reagents. Herein, we report a new practical, mild, high-yielding, and supporting-electrolyte-free electrochemical… read more here.
Keywords: primary amines; isothiocyanation primary; electrochemical isothiocyanation;
Photoredox/Copper-Catalyzed One-Pot Aminoalkylation/Cyclization of Alkenes with Primary Amines to Synthesize Polysubstituted γ-Lactams.
Sign Up to like & getrecommendations! Published in 2024 at "Organic letters"
DOI: 10.1021/acs.orglett.3c03974
Abstract: Visible-light-driven chemical transformation has emerged as a powerful tool for the synthesis of γ-lactams. However, during this transformation, the α-bromoimides need to be pre-prepared. Herein, we report a photoreodox/copper-catalyzed one-pot three-component reaction of alkenes with… read more here.
Keywords: alkenes primary; one pot; primary amines; copper catalyzed ... See more keywords
Ambient-Temperature Synthesis of Primary Amines via Reductive Amination of Carbonyl Compounds
Sign Up to like & getrecommendations! Published in 2020 at "ACS Catalysis"
DOI: 10.1021/acscatal.0c01872
Abstract: Efficient synthesis of primary amines via low-temperature reductive amination of carbonyl compounds using NH3 and H2 as the nitrogen and hydrogen resources is highly desired and challenging in the ... read more here.
Keywords: primary amines; amines via; synthesis primary; carbonyl compounds ... See more keywords