miR-155 as a potential target of IL-3 signaling in primary AML cells.
Sign Up to like & getrecommendations! Published in 2017 at "Leukemia research"
DOI: 10.1016/j.leukres.2017.02.010
Abstract: miR-155 has emerged as one of the key microRNAs (miRNAs) involved in normal and malignant myelopoiesis, and high expression of this miRNA has been flagged as a strong independent prognostic marker in Acute Myeloid Leukemia… read more here.
Keywords: mir 155; target signaling; primary aml; aml cells ... See more keywords
Abstract 5798: Ex vivo culturing of primary AML cells facilitates the study of developmental therapeutics
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-5798
Abstract: Studies with acute myeloid leukemia (AML) cell lines have limited potential as they tend to acquire mutations, thus, do not represent typical leukemias found in patients. Ex vivo culturing of primary human AML patient cells… read more here.
Keywords: culture; culturing primary; cell; aml cells ... See more keywords
Direct Comparison of in-Vitro Growth of Primary Human Acute Myeloid Leukemia (AML) Cells in Stromal and Stromal-Free Conditions
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DOI: 10.1182/blood-2018-99-116978
Abstract: Background: Acute myeloid leukemia (AML) is a very aggressive bone marrow malignancy which carries a poor prognosis despite intensive chemotherapy. The treatment of relapsed and refractory AML remains suboptimal. Although more novel therapies are being… read more here.
Keywords: comparison; primary aml; aml cells; aml ... See more keywords