Methylene blue regulates inflammatory response in osteoarthritis by noncoding long chain RNA CILinc02
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27602
Abstract: Long noncoding RNAs serve as novel regulatory molecules involved in various biological processes, but their role in osteoarthritis (OA) remains unknown. Therefore, we aimed to reveal the inflammatory mechanisms regulated by CILinc02 and methylene blue… read more here.
Keywords: cilinc02; cilinc02 methylene; methylene blue; inflammatory response ... See more keywords
Investigation of essential cell cycle regulator genes as candidates for immortalized shrimp cell line establishment based on the effect of in vitro culturing on gene expression of shrimp primary cells
Sign Up to like & getrecommendations! Published in 2020 at "Aquaculture"
DOI: 10.1016/j.aquaculture.2020.735733
Abstract: Abstract Continuous shrimp cell cultures offer opportunities for studying shrimp pathogens at the cellular and molecular level and developing diagnostic tools. However, no continuous shrimp cell lines have yet been successfully established. This might be… read more here.
Keywords: shrimp cell; cell cycle; primary cells; gene ... See more keywords
Epigallocatechin-3-gallate exhibits immunomodulatory effects in human primary T cells.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.02.132
Abstract: T cells secrete several inflammatory cytokines that play a critical role in the progression of atherosclerosis. Although green tea epigallocatechin-3-gallate (EGCG) exerts anti-inflammatory and anti-atherosclerotic effects in animals, few studies have identified the mechanism underlying… read more here.
Keywords: gallate exhibits; human primary; epigallocatechin gallate; primary cells ... See more keywords
Electrochemical impedance studies of Na/MnO2 primary cells
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Electroanalytical Chemistry"
DOI: 10.1016/j.jelechem.2017.05.038
Abstract: Abstract Primary Na/MnO 2 cells are expected to gain importance for replacement of primary Li/MnO 2 cells in future akin to the Na-ion cells as alternative for Li-ion cells. Amorphous MnO 2 is prepared by… read more here.
Keywords: impedance studies; electrochemical impedance; primary cells; impedance ... See more keywords
RNAseq analysis identifies involvement of EBNA2 in PD-L1 induction during Epstein-Barr virus infection of primary B cells.
Sign Up to like & getrecommendations! Published in 2021 at "Virology"
DOI: 10.1016/j.virol.2021.02.004
Abstract: Epstein-Barr virus (EBV) is a causative agent of infectious mononucleosis and several types of malignancy. RNAseq of peripheral blood primary B cell samples infected with wild-type EBV revealed that expression of programmed cell death ligand-1… read more here.
Keywords: epstein barr; infection primary; infection; barr virus ... See more keywords
The anti-osteosarcoma cell activity by the sphingosine kinase 1 inhibitor SKI-V
Sign Up to like & getrecommendations! Published in 2022 at "Cell Death Discovery"
DOI: 10.1038/s41420-022-00838-4
Abstract: Sphingosine kinase 1 (SphK1) expression and activity are elevated in human osteosarcoma (OS) and is a promising target of therapy. SKI-V is a non-competitive and highly-efficient non-lipid SphK1 inhibitor. The potential anti-OS cell activity by… read more here.
Keywords: sphingosine kinase; primary cells; cell activity; inhibitor ... See more keywords
Proteomic analysis in primary T cells reveals IL-7 alters T cell receptor thresholding via CYTIP/cytohesin/LFA-1 localisation and activation
Sign Up to like & getrecommendations! Published in 2022 at "Biochemical Journal"
DOI: 10.1042/bcj20210313
Abstract: The ability of the cellular immune system to discriminate self from foreign antigens depends on the appropriate calibration of the T cell receptor (TCR) signalling threshold. The lymphocyte homeostatic cytokine interleukin 7 (IL-7) is known… read more here.
Keywords: cytip; cytohesin; primary cells; lfa ... See more keywords
T cell receptor engineering of primary NK cells to therapeutically target tumors and tumor immune evasion
Sign Up to like & getrecommendations! Published in 2022 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2021-003715
Abstract: Background T cell receptor (TCR)-engineered cells can be powerful tools in the treatment of malignancies. However, tumor resistance by Human Leukocyte antigen (HLA) class I downregulation can negatively impact the success of any TCR-mediated cell… read more here.
Keywords: target tumors; cell; tcr; primary cells ... See more keywords
Abstract 785: Application of CRISPR/Cas9 gene editing to primary T cells
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-785
Abstract: T cells mediate a broad range of immune responses, especially generation of adaptive immunity for cancer cell clearance. Identification of genetic components that modulate T cell proliferation, differentiation, migration and cytotoxicity would facilitate development of… read more here.
Keywords: crispr cas9; editing primary; primary cells; gene ... See more keywords
CD38 Knockout Primary NK Cells to Prevent "Fratricide" and Boost Daratumumab Activity
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood-2019-129456
Abstract: Multiple myeloma (MM) is a plasma cell neoplasm typically characterized by high and uniform CD38 expression. Daratumumab (DARA), a humanized monoclonal antibody targeting CD38 has dramatically improved the outcome of patients with refractory MM, but… read more here.
Keywords: cd38ko cells; primary cells; dara; cd38 ... See more keywords
Development of a 3D in vitro co-culture model of the airway mucosa using human primary cells
Sign Up to like & getrecommendations! Published in 2021 at "ERJ Open Research"
DOI: 10.1183/23120541.lsc-2021.30
Abstract: More than one billion people worldwide suffer from congenital and chronic respiratory diseases, leading to high rates in mortality and morbidity. The unpredictability of disease progression and responsiveness towards treatment requires sophisticated experimental models to… read more here.
Keywords: development vitro; primary cells; culture model; human primary ... See more keywords