Outcomes Associated With Thiotepa-Based Conditioning in Patients With Primary Central Nervous System Lymphoma After Autologous Hematopoietic Cell Transplant.
Sign Up to like & getrecommendations! Published in 2021 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2021.1074
Abstract: Importance Primary central nervous system lymphoma (PCNSL) requires induction and consolidation to achieve potential cure. High-dose therapy and autologous hematopoietic cell transplant (AHCT) is an accepted and effective consolidation strategy for PCNSL, but no consensus… read more here.
Keywords: nervous system; central nervous; cohort; primary central ... See more keywords
New genetic prognostic biomarkers in primary central nervous system lymphoma (PCNSL)
Sign Up to like & getrecommendations! Published in 2021 at "Brain and Behavior"
DOI: 10.1002/brb3.2061
Abstract: PCNSL is a rare extranodal NHL with poor prognosis. Tumorigenesis has been associated with hyperactivation of BCR downstream and NFkB pathways. We studied the prognosis of the relative expression profile of target genes of NFkB… read more here.
Keywords: genetic prognostic; new genetic; central nervous; prognostic biomarkers ... See more keywords
CD79B Y196 mutation is a potent predictive marker for favorable response to R‐MPV in primary central nervous system lymphoma
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5512
Abstract: Rituximab, high‐dose methotrexate (HD‐MTX), procarbazine and vincristine (R‐MPV), has significantly prolonged the survival of patients with primary central nervous system lymphoma (PCNSL), but predictive factors for response to R‐MPV have not yet been investigated. Herein,… read more here.
Keywords: primary central; mpv; central nervous; system lymphoma ... See more keywords
Radiomic prediction for durable response to high‐dose methotrexate‐based chemotherapy in primary central nervous system lymphoma
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Medicine"
DOI: 10.1002/cam4.70182
Abstract: The rarity of primary central nervous system lymphoma (PCNSL) and treatment heterogeneity contributes to a lack of prognostic models for evaluating posttreatment remission. This study aimed to develop and validate radiomic‐based models to predict the… read more here.
Keywords: central nervous; nervous system; response high; system lymphoma ... See more keywords
Role of vitreous cytology in the diagnosis of primary central nervous system lymphoma: A report of an unusual presentation.
Sign Up to like & getrecommendations! Published in 2023 at "Diagnostic cytopathology"
DOI: 10.1002/dc.25152
Abstract: Primary central nervous system lymphoma (PCNSL) is a rare subtype of non-Hodgkin lymphoma confined to the brain, spinal cord, meninges, intraocular compartment, and cranial nerves. Intraocular lymphoma (IOL) is a rare subtype of PCNSL. Intravitreal… read more here.
Keywords: primary central; central nervous; vitreous cytology; system lymphoma ... See more keywords
Primary central nervous system lymphoma: A curable disease
Sign Up to like & getrecommendations! Published in 2019 at "Hematological Oncology"
DOI: 10.1002/hon.2598
Abstract: Primary central nervous system lymphoma is a rare subtype of non‐Hodgkin lymphoma that is confined to the brain, leptomeninges, or the eye and is associated with a relatively poor prognosis compared to other extranodal diffuse… read more here.
Keywords: system lymphoma; nervous system; central nervous; primary central ... See more keywords
Complications of intracerebroventricular chemotherapy via subgaleal reservoir in primary central nervous system lymphoma: A single‐institution experience on 1247 installations in 94 consecutive patients
Sign Up to like & getrecommendations! Published in 2020 at "Hematological Oncology"
DOI: 10.1002/hon.2833
Abstract: The implantation of a subgaleal reservoir intracerebroventricular (ICV port) in order to apply ICV chemotherapy in patients with leptomeningeal cancer may be complicated by misplacement of the device, pericatheter leucencephalopathy, hemorrhage and iatrogenic ventriculitis/meningitis. Here… read more here.
Keywords: chemotherapy; system lymphoma; nervous system; central nervous ... See more keywords
Combined tumor-associated macrophages biomarker predicting extremely poor outcome of patients with primary central nervous system lymphoma.
Sign Up to like & getrecommendations! Published in 2021 at "Hematological oncology"
DOI: 10.1002/hon.2926
Abstract: Primary central nervous system lymphoma (PCNSL) is an aggressive and rare malignancy with poor prognosis. However, there are no reliable prognostic biomarkers for PCNSL in clinical practice. Here, we aimed to identify a reliable prognostic… read more here.
Keywords: nervous system; central nervous; primary central; ielsg index ... See more keywords
Multiparametric‐MRI‐Based Radiomics Model for Differentiating Primary Central Nervous System Lymphoma From Glioblastoma: Development and Cross‐Vendor Validation
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.27344
Abstract: Preoperative differentiation of primary central nervous system lymphoma (PCNSL) from glioblastoma (GBM) is important to guide neurosurgical decision‐making. read more here.
Keywords: glioblastoma; system lymphoma; nervous system; central nervous ... See more keywords
Detecting B-cell lymphoma-6 overexpression status in primary central nervous system lymphoma using multiparametric MRI-based machine learning
Sign Up to like & getrecommendations! Published in 2025 at "Neuroradiology"
DOI: 10.1007/s00234-025-03551-y
Abstract: In primary central nervous system lymphoma (PCNSL), B-cell lymphoma-6 (BCL-6) is an unfavorable prognostic biomarker. We aim to non-invasively detect BCL-6 overexpression in PCNSL patients using multiparametric MRI and machine learning techniques. 65 patients (101… read more here.
Keywords: central nervous; nervous system; machine learning; machine ... See more keywords
Interim 18F-FGD PET/CT may not predict the outcome in primary central nervous system lymphoma patients treated with sequential treatment with methotrexate and cytarabine
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Hematology"
DOI: 10.1007/s00277-017-3068-9
Abstract: Abstract18F-fluoro-2-dexoy-D-glucose-positron emission tomography (PET)/computed tomography (CT) is a useful imaging technique for monitoring the treatment response in lymphoma cases. We investigated the value of interim brain PET/CT (I-PET/CT) for monitoring the response to intensive methotrexate-based… read more here.
Keywords: pet; methotrexate; central nervous; primary central ... See more keywords