Craniotomy versus biopsy for primary CNS lymphoma: An institutional series and nationwide NCDB‐PUF and SEER database study
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DOI: 10.1002/hon.2439_108
Abstract: (p < 0.0001) as the most important variables predicting better survival at diagnosis. However, in the multivariate analysis, only age ≤ 60 years (p < 0.005), male sex (p = 0.04) and ECOG read more here.
Keywords: cns lymphoma; craniotomy versus; lymphoma institutional; versus biopsy ... See more keywords
CSF interleukin 6 is a useful marker to distinguish pseudotumoral CNS inflammatory diseases from primary CNS lymphoma
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Neurology"
DOI: 10.1007/s00415-021-10453-5
Abstract: Interleukin 6 (IL-6) is a pleomorphic cytokine that can be found in the cerebrospinal fluid (CSF) in a wide spectrum of inflammatory pathologies of the central nervous system (CNS). Our aim was to characterize the… read more here.
Keywords: cns lymphoma; cns; inflammatory diseases; csf ... See more keywords
Diagnosis, treatment, and outcome of primary CNS lymphoma—a single-center experience
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DOI: 10.1007/s00701-022-05170-5
Abstract: Primary CNS lymphoma (PCNSL) is a highly aggressive non-Hodgkin lymphoma (NHL) that occurs in the CNS (e.g. brain, meninges, spinal cord, cerebrospinal fluid, or intraocular involvement) in the absence of systemic NHL. Tumor resection does… read more here.
Keywords: primary cns; lymphoma; cns lymphoma; single center ... See more keywords
DICER1 mutations in primary central nervous system tumors: new insights into histologies, mutations, and prognosis
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DOI: 10.1007/s11060-022-03994-w
Abstract: We sought to characterize clinical outcomes for adult and pediatric patients with primary CNS tumors harboring DICER1 mutations or loss of DICER1. We conducted a retrospective cohort study of 98 patients who were treated between… read more here.
Keywords: cns tumors; glioma; dicer1 mutations; grade glioma ... See more keywords
Persistent hiccups and Horner’s syndrome in a case of primary CNS lymphoma with diffuse cerebral, hypothalamic and lateral brainstem involvement – An exercise in clinical neuroanatomy
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Neuroscience"
DOI: 10.1016/j.jocn.2020.09.061
Abstract: We present a case of a 42-year-old male presenting with persistent hiccups and a Horner's syndrome, among other symptoms and signs of hypothalamic and brainstem dysfunction. He had a biopsy-proven diffuse infiltrative large primary CNS… read more here.
Keywords: horner syndrome; hiccups horner; persistent hiccups; case ... See more keywords
Have treatment protocols for primary CNS lymphoma advanced in the past 10 years
Sign Up to like & getrecommendations! Published in 2019 at "Expert Review of Anticancer Therapy"
DOI: 10.1080/14737140.2019.1677157
Abstract: ABSTRACT Introduction: Primary CNS lymphomas (PCNSL) are highly aggressive tumors and optimal treatment is not yet defined. For the last two decades, clinical trials have focused on developing efficient chemotherapy protocols with or without dose-reduced… read more here.
Keywords: chemotherapy; cns lymphoma; treatment protocols; treatment ... See more keywords
CNSC-37. ATYPICAL GERMLINE MUTATIONS AND PRIMARY CNS TUMORS: A SINGLE-CENTER CASE SERIES AND LITERATURE REVIEW
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DOI: 10.1093/neuonc/noac209.117
Abstract: A growing spectrum of germline mutations and their association with primary CNS tumors has been described over the last decade. These germline mutations are implicated in regulation of DNA integrity and repair, telomere maintenance, and… read more here.
Keywords: germline; case series; germline mutations; atypical germline ... See more keywords
Temporalis muscle thickness predicts early relapse and short survival in primary CNS lymphoma.
Sign Up to like & getrecommendations! Published in 2022 at "Neuro-oncology practice"
DOI: 10.1093/nop/npac087
Abstract: Background Most patients with primary CNS lymphoma (PCNSL) achieve durable remission whereas a minority die in the first year. Sarcopenia is a powerful predictor of mortality in the brain and systemic cancers. Temporalis muscle thickness… read more here.
Keywords: oncology; thin tmt; survival; short survival ... See more keywords
Sustained Complete Remission in Multi-Relapsed Primary CNS Lymphoma Treated with Ibrutinib Monotherapy: A Case Report
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DOI: 10.1159/000518528
Abstract: Primary CNS lymphoma (PCNSL) is a highly aggressive malignant disease with a high recurrence rate and a poor prognosis. We present the case of a 71-year-old woman diagnosed with PCNSL in June 2010. After 3… read more here.
Keywords: complete remission; cns lymphoma; primary cns; case ... See more keywords
Management and outcome of primary CNS lymphoma in the modern era
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DOI: 10.1212/wnl.0000000000008900
Abstract: Objective Real-life studies on patients with primary CNS lymphoma (PCNSL) are scarce. Our objective was to analyze, in a nationwide population-based study, the current medical practice in the management of PCNSL. Methods The French oculo-cerebral… read more here.
Keywords: management; cns lymphoma; lymphoma; hct asct ... See more keywords
Teaching NeuroImage: Primary CNS Vasculitis Mimicking Intracranial Tumor
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DOI: 10.1212/wnl.0000000000206889
Abstract: A 21-year-old man with headache, vomiting, and limb weakness presented to the clinic 2 years ago. An examination showed paresthesia and weakness in left upper and lower limbs. An examination of the brain MRI demonstrated… read more here.
Keywords: vasculitis; cns vasculitis; cns; teaching neuroimage ... See more keywords