IGF-1-Mediated Survival from Induced Death of Human Primary Cultured Retinal Pigment Epithelial Cells Is Mediated by an Akt-Dependent Signaling Pathway
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Neurobiology"
DOI: 10.1007/s12035-017-0447-0
Abstract: Degeneration of the human retinal pigmented epithelium (hRPE) is involved in several eye disorders such as age-related macular degeneration (AMD). In this study, we investigated the protective effect of IGF-1 on human primary cultured RPE… read more here.
Keywords: akt; rpe cells; effect; igf ... See more keywords
Therapeutic potential of d-cysteine against in vitro and in vivo models of spinocerebellar ataxia
Sign Up to like & getrecommendations! Published in 2021 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2021.113791
Abstract: Spinocerebellar ataxia (SCA) is a group of autosomal-dominantly inherited ataxia and is classified into SCA1-48 by the difference of causal genes. Several SCA-causing proteins commonly impair dendritic development in primary cultured Purkinje cells (PCs). We… read more here.
Keywords: spinocerebellar ataxia; vivo; cysteine; sca ... See more keywords
2,3,7,8-Tetrachlorodibenzo-p-dioxin promotes migration ability of primary cultured rat astrocytes via aryl hydrocarbon receptor.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of environmental sciences"
DOI: 10.1016/j.jes.2018.05.030
Abstract: Emerging evidence showed that 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) could induce expression of certain reactivation-associated genes in astrocytes, however, the consequent cellular effects and molecular mechanisms are still unclear. During the process of astrocyte reactivation, migration is a… read more here.
Keywords: dioxin; ability primary; migration; tetrachlorodibenzo dioxin ... See more keywords
Investigating the expression of pluripotency-related genes in human amniotic fluid cells: A semi-quantitative comparison between different subpopulations, from primary to cultured amniocytes.
Sign Up to like & getrecommendations! Published in 2020 at "Reproductive biology"
DOI: 10.1016/j.repbio.2020.05.005
Abstract: Various classifications have been proposed for human amniotic subpopulations, including classification of spindle-shaped (SS) and round-shaped (RS) cells, as well as the more referred triple-category of epithelioid (E-type) cells, amniotic fluid-specific (AF-type) cells and fibroblastoid… read more here.
Keywords: cultured amniocytes; expression; human amniotic; amniotic fluid ... See more keywords
Translation imaging of single mRNAs in established cell lines and primary cultured neurons.
Sign Up to like & getrecommendations! Published in 2019 at "Methods"
DOI: 10.1016/j.ymeth.2019.03.021
Abstract: The central dogma of molecular biology reaches a crescendo at its final step: the translation of an mRNA into its corresponding protein product. This process is highly regulated both spatially and temporally, requiring techniques to… read more here.
Keywords: lines primary; cell lines; single mrnas; established cell ... See more keywords
Identification of the expression of farnesoid X receptor in astrocytes
Sign Up to like & getrecommendations! Published in 2021 at "NeuroReport"
DOI: 10.1097/wnr.0000000000001717
Abstract: Recently, we have identified a functional expression of farnesoid X receptor (FXR) in neurons in vitro and in vivo. However, whether the FXR is expressed in astrocytes remains unclear. In the present study, we addressed… read more here.
Keywords: expression; expression farnesoid; farnesoid receptor; cultured astrocytes ... See more keywords
Suppression of testosterone production by nanoparticulate TiO2 is associated with ERK1/2–PKA–PKC signaling pathways in rat primary cultured Leydig cells
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s175608
Abstract: Background Nanoparticulate titanium dioxide (nano-TiO2) enters the body through various routes and causes organ damage. Exposure to nano-TiO2 is reported to cause testicular injury in mice or rats and decrease testosterone synthesis, sperm number, and… read more here.
Keywords: tio2; nano tio2; testosterone production; primary cultured ... See more keywords
The Effects of Inorganic Phosphorus Levels on Phosphorus Utilization, Local Bone-Derived Regulators, and BMP/MAPK Pathway in Primary Cultured Osteoblasts of Broiler Chicks
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2022.855405
Abstract: Understanding the underlying mechanisms that regulate the bone phosphorus (P) utilization would be helpful for developing feasible strategies to improve utilization efficiency of P in poultry. We aimed to investigate the effects of inorganic P… read more here.
Keywords: broiler chicks; bone; local bone; primary cultured ... See more keywords