Multi-omic analysis in carcinoma of unknown primary (CUP): therapeutic impact of knowing the unknown.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular oncology"
DOI: 10.1002/1878-0261.13293
Abstract: Carcinoma of unknown primary (CUP) is a difficult-to-manage malignancy. Multi-omic profiles and treatment outcome versus degree of precision matching was assessed. Tumors underwent next-generation sequencing (NGS) [tissue and/or blood-derived cell-free DNA (cfDNA)]. Selected patients had… read more here.
Keywords: cup; unknown primary; multi omic; analysis ... See more keywords
Cancer of unknown primary (CUP) with disseminated-lymphadenopathy presentation: Clinicopathological features, prognostic factors, and survival outcomes.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.4_suppl.465
Abstract: 465Background: Aside from traditional favorable localized-nodal CUP (LNC) subsets including solitary nodal disease, women with isolated axillary adenocarcinoma and squamous cell carcinoma of cervical/inguinal lymph nodes, there is limited data on disseminated nodal CUP (DNC)… read more here.
Keywords: primary cup; presentation; nodal cup; cancer unknown ... See more keywords
The Quest for Improving Treatment of Cancer of Unknown Primary (CUP) Through Molecularly-Driven Treatments: A Systematic Review
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2020.00533
Abstract: Background: Carcinomas of unknown primary (CUP) account for 3–5% of all malignancy and, despite a reduction in incidence, the overall survival has not improved over the last decade. Chemotherapy regimens have not provided encouraging results.… read more here.
Keywords: primary cup; treatment; systematic review; unknown primary ... See more keywords