ROS mediated apoptotic pathways in primary effusion lymphoma: Comment on induction of apoptosis by Shikonin through ROS-mediated intrinsic and extrinsic pathways in primary effusion lymphoma
Sign Up to like & getrecommendations! Published in 2021 at "Translational Oncology"
DOI: 10.1016/j.tranon.2021.101061
Abstract: Highlights • Mechanism of action of Shikonin against PEL.• Therapeutic potential of Shikonin as an alternative herbal medicine.• Interconnectivity among cellular stress, apoptosis pathways (extrinsic and intrinsic) and Shikonin. read more here.
Keywords: pathways primary; ros mediated; shikonin; primary effusion ... See more keywords
Primary effusion lymphoma enhancer connectome links super-enhancers to dependency factors
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-20136-w
Abstract: Primary effusion lymphoma (PEL) has a very poor prognosis. To evaluate the contributions of enhancers/promoters interactions to PEL cell growth and survival, here we produce H3K27ac HiChIP datasets in PEL cells. This allows us to… read more here.
Keywords: enhancer connectome; dependency factors; connectome links; primary effusion ... See more keywords
Inhibition of MCL1 induces apoptosis in anaplastic large cell lymphoma and in primary effusion lymphoma
Sign Up to like & getrecommendations! Published in 2022 at "Scientific Reports"
DOI: 10.1038/s41598-022-04916-6
Abstract: Overexpression of antiapoptotic BCL2 family proteins occurs in various hematologic malignancies and contributes to tumorigenesis by inhibiting the apoptotic machinery of the cells. Antagonizing BH3 mimetics provide an option for medication, with venetoclax as the… read more here.
Keywords: cell lymphoma; primary effusion; lymphoma; anaplastic large ... See more keywords
Human herpes virus 8-unrelated primary effusion lymphoma-like lymphoma presenting with cardiac tamponade
Sign Up to like & getrecommendations! Published in 2017 at "Medicine"
DOI: 10.1097/md.0000000000008010
Abstract: Rationale: Primary effusion lymphoma (PEL) is a rare disease of lymphomatous effusion in the body cavities in the absence of detectable mass and lymphadenopathy. PEL is predominantly related to the immunosuppressed patients infected with human… read more here.
Keywords: lymphoma; like lymphoma; primary effusion; effusion lymphoma ... See more keywords
Rapidly progressive intravascular primary effusion lymphoma in an HIV‐positive renal transplant recipient
Sign Up to like & getrecommendations! Published in 2018 at "Histopathology"
DOI: 10.1111/his.13347
Abstract: We describe the clinical and post‐mortem findings of a case of rapidly progressive, ultimately fatal primary effusion lymphoma (PEL) arising in an HIV‐positive man 2 years after renal transplantation. Disseminated multi‐organ involvement associated with a… read more here.
Keywords: lymphoma; rapidly progressive; primary effusion; effusion lymphoma ... See more keywords
Primary effusion lymphoma of the pleural space: Report of a rare complication of cardiac transplant with review of the literature
Sign Up to like & getrecommendations! Published in 2019 at "Transplant Infectious Disease"
DOI: 10.1111/tid.13005
Abstract: Primary effusion lymphoma (PEL) is a rare mature B‐cell non‐Hodgkin’s lymphoma arising in body cavities and presenting with effusions. It has been described predominantly in patients with impaired immunity from the acquired immunodeficiency syndrome and… read more here.
Keywords: effusion lymphoma; transplant; report; primary effusion ... See more keywords
Expression Ratios of the Antiapoptotic BCL2 Family Members Dictate the Selective Addiction of Kaposi’s Sarcoma-Associated Herpesvirus-Transformed Primary Effusion Lymphoma Cell Lines to MCL1
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.01360-22
Abstract: Primary effusion lymphoma (PEL) is caused by Kaposi’s sarcoma-associated herpesvirus. We showed previously that PEL cell lines require the antiapoptotic protein MCL1 for survival but not the other BCL2 family proteins. ABSTRACT Kaposi’s sarcoma-associated herpesvirus… read more here.
Keywords: bcl2 family; mcl1; family; primary effusion ... See more keywords
Synchronous visceral Kaposi sarcoma and extracavitary primary effusion lymphoma in a patient with AIDS
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DOI: 10.1136/bcr-2021-245306
Abstract: While infection should always lead the differential when a patient with AIDS presents with fever, inflammatory and malignant aetiologies should also be considered. With profound immunocompromise, malignancies can develop as sequelae of viral oncogene expression.… read more here.
Keywords: synchronous visceral; effusion lymphoma; kaposi sarcoma; primary effusion ... See more keywords
Abstract 6751: Provisional prognostic score for primary effusion lymphoma
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-6751
Abstract: Background Primary effusion lymphoma (PEL) is a rare and aggressive type of B-cell non-Hodgkin lymphoma presenting primarily as lymphomatous effusions in body cavities and less often as solid extracavitary masses. It is typically associated with… read more here.
Keywords: lymphoma; prognostic score; risk; primary effusion ... See more keywords
Kaposi Sarcoma With Intravascular Primary Effusion Lymphoma in the Skin: A Potential Pitfall in HHV8 Immunohistochemistry Interpretation
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DOI: 10.1177/1066896920917212
Abstract: Primary effusion lymphoma is a rare, clinically aggressive large B-cell neoplasm universally associated with human herpesvirus 8 that occurs in the setting of immune compromise. It is classically described as a lymphomatous effusion occurring within… read more here.
Keywords: effusion lymphoma; kaposi sarcoma; pathology; primary effusion ... See more keywords
Extracavitary Primary Effusion Lymphoma Affecting the Oral Cavity: A Rare Case Report.
Sign Up to like & getrecommendations! Published in 2023 at "International journal of surgical pathology"
DOI: 10.1177/10668969231167509
Abstract: Primary effusion lymphoma (PEL) is an aggressive neoplasm often diagnosed in immunosuppressed patients demonstrating peritoneal, pleural, or pericardial effusions. This high-grade lymphoma is strongly associated with human herpesvirus 8 (HHV8) infection and most of the… read more here.
Keywords: lymphoma; effusion lymphoma; report; primary effusion ... See more keywords