Identification of N6-methyladenosine-related lncRNAs for patients with primary glioblastoma
Sign Up to like & getrecommendations! Published in 2020 at "Neurosurgical Review"
DOI: 10.1007/s10143-020-01238-x
Abstract: To investigate the m 6 a-related long non-coding RNAs (lncRNAs) that may be exploited as potential biomarkers in primary glioblastoma (pGBM), a cohort of 268 glioma samples from GSE16011 dataset was included for discovery. The… read more here.
Keywords: identification methyladenosine; risk group; risk; primary glioblastoma ... See more keywords
319 Phase II trial of immunotherapy in primary glioblastoma: antigens from self-renewing autologous tumor cells presented by autologous dendritic cell vaccine
Sign Up to like & getrecommendations! Published in 2020 at "Journal for ImmunoTherapy of Cancer"
DOI: 10.1136/jitc-2020-sitc2020.0319
Abstract: Background Primary glioblastoma (GBM) is associated with poor survival. Adjunctive vaccines may improve survival by inducing or enhancing anti-GBM immune responses. Methods A multi-institutional phase II clinical trial was conducted with a primary objective of… read more here.
Keywords: phase; trial; primary glioblastoma; cell ... See more keywords
In Vitro/In Silico Study on the Role of Doubling Time Heterogeneity among Primary Glioblastoma Cell Lines
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DOI: 10.1155/2017/8569328
Abstract: The application of accurate cancer predictive algorithms validated with experimental data is a field concerning both basic researchers and clinicians, especially regarding a highly aggressive form of cancer, such as Glioblastoma. In an aim to… read more here.
Keywords: glioblastoma; primary glioblastoma; cell lines; heterogeneity ... See more keywords
MGMT Promoter Methylation as a Prognostic Factor in Primary Glioblastoma: A Single-Institution Observational Study
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10082030
Abstract: Glioblastoma is the most malignant central nervous system tumor, which represents 50% of all glial tumors. The understanding of glioma genesis, prognostic evaluation, and treatment planning has been significantly enhanced by the discovery of molecular… read more here.
Keywords: methylation; promoter methylation; mgmt promoter; primary glioblastoma ... See more keywords
Potential Prognostic Value of GATA4 Depends on the p53 Expression in Primary Glioblastoma Patients
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DOI: 10.3390/genes14061146
Abstract: Background: Primary glioblastoma is characterized by an extremely poor prognosis. The promoter methylation of GATA4 leads to the loss of its expression in many cancer types. The formation of high-grade astrocytomas can be promoted by… read more here.
Keywords: promoter; gata4; p53 expression; primary glioblastoma ... See more keywords