High Pre-Donation Vasoactive Inotropic Score (VIS) May Be Associated with Increased Risk of Primary Graft Dysfunction in Cardiac Transplantation
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Heart and Lung Transplantation"
DOI: 10.1016/j.healun.2021.01.653
Abstract: Purpose Primary Graft Dysfunction (PGD) is one of the primary causes of 30 day mortality after heart transplantation. Optimal donor management is crucial to ensure effective organ procurement and favourable transplant outcomes. The prognostic impact… read more here.
Keywords: primary graft; transplantation; pre donation; graft dysfunction ... See more keywords
Serum biomarkers for primary graft failure in pediatric heart transplantation
Sign Up to like & getrecommendations! Published in 2017 at "Progress in Pediatric Cardiology"
DOI: 10.1016/j.ppedcard.2017.06.008
Abstract: Abstract Primary graft failure has been broadly defined as cardiac and circulatory insufficiency in the immediate postoperative period after cardiac transplantation. Risk factors for primary graft failure have been identified in the donor, recipient, and… read more here.
Keywords: graft failure; transplantation; serum biomarkers; primary graft ... See more keywords
Pre-existing self-reactive IgA antibodies associated with primary graft dysfunction after lung transplantation.
Sign Up to like & getrecommendations! Published in 2020 at "Transplant immunology"
DOI: 10.1016/j.trim.2020.101271
Abstract: BACKGROUND Primary graft Dysfunction (PGD) results in significant mortality and morbidity after lung transplantation (LT). The objective of this study was to evaluate if pre-existing antibodies to self-antigens in sera of LT recipients are associated… read more here.
Keywords: pre existing; iga; transplantation; primary graft ... See more keywords
Pro-inflammatory IgG1 N-glycan signature correlates with primary graft dysfunction onset in COPD patients.
Sign Up to like & getrecommendations! Published in 2021 at "Transplant immunology"
DOI: 10.1016/j.trim.2021.101491
Abstract: Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide. The pathogenesis of COPD is complex; however, recent studies suggest autoimmune changes, characterized by the presence of autoantibodies to elastin and collagen,… read more here.
Keywords: copd patients; graft dysfunction; antibody; copd ... See more keywords
Volatile organic compound profiling to explore primary graft dysfunction after lung transplantation
Sign Up to like & getrecommendations! Published in 2022 at "Scientific Reports"
DOI: 10.1038/s41598-022-05994-2
Abstract: Primary graft dysfunction (PGD) is a major determinant of morbidity and mortality following lung transplantation. Delineating basic mechanisms and molecular signatures of PGD remain a fundamental challenge. This pilot study examines if the pulmonary volatile… read more here.
Keywords: pgd; graft dysfunction; lung transplantation; transplantation ... See more keywords
Short-term mechanical circulatory support for severe primary graft dysfunction following orthotopic heart transplant.
Sign Up to like & getrecommendations! Published in 2018 at "Interactive cardiovascular and thoracic surgery"
DOI: 10.1093/icvts/ivy050
Abstract: OBJECTIVES Primary graft dysfunction (PGD) is a devastating complication and the most common cause of early death following a heart transplant. The goal of this study was to report our experience of using mechanical circulatory… read more here.
Keywords: heart transplant; assist device; primary graft; support ... See more keywords
Primary Graft Dysfunction in Heart Transplant Recipients—Risk Factors and Longitudinal Outcomes
Sign Up to like & getrecommendations! Published in 2021 at "ASAIO Journal"
DOI: 10.1097/mat.0000000000001469
Abstract: Supplemental Digital Content is available in the text. Before the 33rd Annual International Society for Heart and Lung Transplantation conference, there was significant intercenter variability in definitions of primary graft dysfunction (PGD). The incidence, risk… read more here.
Keywords: heart; graft dysfunction; risk factors; pgd ... See more keywords
Primary graft dysfunction in heart transplantation
Sign Up to like & getrecommendations! Published in 2018 at "Current Opinion in Organ Transplantation"
DOI: 10.1097/mot.0000000000000523
Abstract: Purpose of review Primary graft dysfunction (PGD) is common early postheart transplantation; however, use of standardized definitions remains inconsistent. This review focuses on understanding the incidence, classification, risk factors, and management of PGD. Recent findings… read more here.
Keywords: heart; graft dysfunction; transplantation; heart transplantation ... See more keywords
Primary graft dysfunction after lung transplantation
Sign Up to like & getrecommendations! Published in 2023 at "Current Opinion in Organ Transplantation"
DOI: 10.1097/mot.0000000000001065
Abstract: Purpose of review Primary graft dysfunction (PGD) is a clinical syndrome occurring within the first 72 h after lung transplantation and is characterized clinically by progressive hypoxemia and radiographically by patchy alveolar infiltrates. Resulting from ischemia-reperfusion… read more here.
Keywords: lung transplantation; primary graft; lung; transplantation ... See more keywords
Primary Graft Dysfunction in Lung Transplantation: A Review of Mechanisms and Future Applications.
Sign Up to like & getrecommendations! Published in 2023 at "Transplantation"
DOI: 10.1097/tp.0000000000004503
Abstract: Lung allograft recipients have worse survival than all other solid organ transplant recipients, largely because of primary graft dysfunction (PGD), a major form of acute lung injury affecting a third of lung recipients within the… read more here.
Keywords: lung transplantation; primary graft; lung; transplantation ... See more keywords
Mitochondrial damage–associated molecular patterns released by lung transplants are associated with primary graft dysfunction
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Transplantation"
DOI: 10.1111/ajt.15232
Abstract: Primary graft dysfunction (PGD) is a major limitation in short‐ and long‐term lung transplant survival. Recent work has shown that mitochondrial damage–associated molecular patterns (mtDAMPs) can promote solid organ injury, but whether they contribute to… read more here.
Keywords: mitochondrial damage; associated molecular; graft dysfunction; damage associated ... See more keywords