Soluble plasma programmed death 1 (PD-1) and Tim-3 in primary HIV infection
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DOI: 10.1097/qad.0000000000002165
Abstract: &NA; Soluble forms of the coinhibitory receptors programmed death 1 (PD-1) and Tim-3 exist, but their relationship with T-cell surface expression remains unclear. When measured by an enzyme-linked immunosorbent assay in plasma, soluble PD-1, and… read more here.
Keywords: hiv infection; tim; primary hiv; death tim ... See more keywords
A Cytokine Pattern That Differentiates Preseroconversion From Postseroconversion Phases of Primary HIV Infection.
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DOI: 10.1097/qai.0000000000001272
Abstract: BACKGROUND During acute HIV infection, HIV actively replicates but seroconversion has not yet occurred. Primary HIV infection (PHI) is characterized by a transient nonspecific febrile illness, a massive inflammatory response, and the progressive appearance of… read more here.
Keywords: hiv infection; cytokine; primary hiv; hiv ... See more keywords
A Longitudinal Analysis Reveals Early Activation and Late Alterations in B Cells During Primary HIV Infection in Mozambican Adults
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DOI: 10.3389/fimmu.2020.614319
Abstract: Primary HIV infection (PHI) and subsequent chronic infection alter B-cell compartment. However, longitudinal analysis defining the dynamics of B-cell alterations are still limited. We longitudinally studied B-cell subsets in individuals followed for 1 year after… read more here.
Keywords: hiv infection; primary hiv; infection; activation ... See more keywords
Virological and Immunological Outcomes of an Intensified Four-Drug versus a Standard Three-Drug Antiretroviral Regimen, Both Integrase Strand Transfer Inhibitor-Based, in Primary HIV Infection
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DOI: 10.3390/ph15040403
Abstract: The optimal therapeutic approach for primary HIV infection (PHI) is still debated. We aimed to compare the viroimmunological response to a four- versus a three-drug regimen, both INSTI-based, in patients with PHI. This was a… read more here.
Keywords: primary hiv; drug; hiv infection; three drug ... See more keywords
Primary HIV Infection in Patients with Acute Hepatitis B: A Report of Two Cases
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DOI: 10.3851/imp3201
Abstract: We describe two patients admitted to our institution with a diagnosis of sexually acquired acute hepatitis B who also had underlying hyper acute HIV infection. Both individuals reported high rates of condomless sex. Antiviral therapy… read more here.
Keywords: hiv infection; infection patients; primary hiv; patients acute ... See more keywords