GVHD, IBD, and primary immunodeficiencies: The gut as a target of immunopathology resulting from impaired immunity
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Immunology"
DOI: 10.1002/eji.202149530
Abstract: The intestinal tract is the largest immunological organ in the body and has a central function of regulating local immune responses, as the intestinal epithelial barrier is a location where the immune system interacts with… read more here.
Keywords: ibd primary; immunopathology; primary immunodeficiencies; impaired immunity ... See more keywords
Periodontal status of children with primary immunodeficiencies: a systematic review
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Oral Investigations"
DOI: 10.1007/s00784-019-03055-z
Abstract: Objective The aim of this systematic review was to appraise the existing literature on periodontal disease in children affected by different types of neutrophil-associated primary immunodeficiencies (PIDs). Methods A PRESS-validated search strategy was developed to… read more here.
Keywords: systematic review; primary immunodeficiencies; children primary; periodontal status ... See more keywords
Targeted genome editing for the correction or alleviation of primary Immunodeficiencies.
Sign Up to like & getrecommendations! Published in 2021 at "Progress in molecular biology and translational science"
DOI: 10.1016/bs.pmbts.2021.03.001
Abstract: Primary immunodeficiencies (PID) are a growing list of unique disorders that result in a failure of the innate/adaptive immune systems to fully respond to disease or infection. PIDs are classified into five broad categories; B… read more here.
Keywords: targeted genome; correction alleviation; genome editing; primary immunodeficiencies ... See more keywords
Eczematous dermatitis in primary immunodeficiencies: A review of cutaneous clues to diagnosis.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical immunology"
DOI: 10.1016/j.clim.2019.108330
Abstract: Primary immunodeficiency Disorders (PIDD) are a varied group of heritable disorders characterized by defects in components of the innate and/or adaptive arms of the immune system. Although diagnosing these disorders is often challenging, the skin… read more here.
Keywords: immunodeficiencies review; dermatitis primary; clues diagnosis; eczematous dermatitis ... See more keywords
Nutritional challenges in children with primary immunodeficiencies undergoing hematopoietic stem cell transplant.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical nutrition"
DOI: 10.1016/j.clnu.2019.12.015
Abstract: Nutritional profile and management of patients with primary immunodeficiencies (PID) undergoing hematopoietic stem cell transplant (HSCT) has not been described in the literature. We aim to report the nutritional challenges and practices peculiar to this… read more here.
Keywords: undergoing hematopoietic; nutritional challenges; stem cell; hematopoietic stem ... See more keywords
Pathogenesis of infections in HIV-infected individuals: insights from primary immunodeficiencies.
Sign Up to like & getrecommendations! Published in 2017 at "Current opinion in immunology"
DOI: 10.1016/j.coi.2017.09.002
Abstract: Following infection with almost any given microorganism other than an emerging pathogen, only a minority of individuals develop life-threatening clinical disease, implying that these individuals have some form of immunodeficiency. A growing number of inherited… read more here.
Keywords: immunology; infections hiv; infection; pathogenesis infections ... See more keywords
Epigenetic Deregulation in Human Primary Immunodeficiencies.
Sign Up to like & getrecommendations! Published in 2019 at "Trends in immunology"
DOI: 10.1016/j.it.2018.11.005
Abstract: Primary immunodeficiencies (PIDs) are immune disorders resulting from defects in genes involved in immune regulation, and manifesting as an increased susceptibility to infections, autoimmunity, and cancer. However, the molecular basis of some prevalent entities remains… read more here.
Keywords: epigenetic deregulation; deregulation human; primary immunodeficiencies; human primary ... See more keywords
[Primary immunodeficiencies in seriously ill children: Report of 3 clinical cases].
Sign Up to like & getrecommendations! Published in 2017 at "Revista chilena de pediatria"
DOI: 10.1016/j.rchipe.2016.07.011
Abstract: Primary immunodeficiency diseases (PID) are congenital disorders secondary to an impaired immune response. Infections, autoimmune disorders, atopy, and lymphoproliferative syndromes are commonly associated with this disorder. OBJECTIVE To present and discuss 3 infants diagnosed with… read more here.
Keywords: month old; disease; patient month; clinical cases ... See more keywords
Knock-out iPSCs for disease and therapy modeling of IL-10 associated primary immunodeficiencies.
Sign Up to like & getrecommendations! Published in 2020 at "Human gene therapy"
DOI: 10.1089/hum.2020.235
Abstract: Samples from patients with rare diseases, such as primary immunodeficiencies, are often limited, which hampers careful analysis of the pathomechanisms involved in immune cell dysregulation. To overcome this issue, induced pluripotent stem cells (iPSCs) represent… read more here.
Keywords: knock; cytokine; disease models; disease ... See more keywords
Challenges in and ideas for diagnosing primary immunodeficiencies in Uganda
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Pediatrics"
DOI: 10.1097/mop.0000000000001182
Abstract: Purpose of review Primary immunodeficiencies (PIDs) lately referred to as inborn errors of immunity, are consequences of mutations that affect the immune integrity and function. Globally, severe PIDs are more common in infants and are… read more here.
Keywords: diagnosis; primary immunodeficiencies; ideas diagnosing; immunodeficiencies uganda ... See more keywords
Primary immunodeficiencies and invasive fungal infection: when to suspect and how to diagnose and manage.
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Infectious Diseases"
DOI: 10.1097/qco.0000000000000593
Abstract: PURPOSE OF REVIEW Invasive fungal infections (IFIs) most often occur secondary to acquired immunodeficiency states such as transplantation, AIDS or immune-modulatory treatment for neoplastic and autoimmune disorders. Apart from these acquired conditions, several primary immunodeficiency… read more here.
Keywords: infection suspect; infection; invasive fungal; primary immunodeficiencies ... See more keywords