Gray matter hypertrophy in primary insomnia: a surface-based morphometric study
Sign Up to like & getrecommendations! Published in 2018 at "Brain Imaging and Behavior"
DOI: 10.1007/s11682-018-9992-z
Abstract: Studies have explored brain structural abnormalities in patients with primary insomnia (PI). However, most of them are based on volumetric measures, in a specific region of interest, and have small sample sizes. Here, we investigated… read more here.
Keywords: based morphometric; surface based; primary insomnia; study ... See more keywords
Melatonin and melatonin agonists as treatments for benzodiazepines and hypnotics withdrawal in patients with primary insomnia. A systematic review.
Sign Up to like & getrecommendations! Published in 2020 at "Drug and alcohol dependence"
DOI: 10.1016/j.drugalcdep.2020.107994
Abstract: BACKGROUND Hypnotics (HYP) and benzodiazepines (BZD) are medicines prescribed for the insomnia treatment. Many patients present difficulties in discontinuing the treatment once established. Melatonin (MLT) has been prescribed as a treatment for BZD/HYP detoxification. AIMS… read more here.
Keywords: primary insomnia; bzd hyp; systematic review; patients primary ... See more keywords
Eszopiclone for the treatment of primary insomnia: a systematic review and meta-analysis of double-blind, randomized, placebo-controlled trials.
Sign Up to like & getrecommendations! Published in 2019 at "Sleep medicine"
DOI: 10.1016/j.sleep.2019.03.016
Abstract: STUDY OBJECTIVE In this study, we performed a systematic review and meta-analysis of double-blind, randomized, placebo-controlled trials to evaluate the efficacy and safety of eszopiclone for the treatment of primary insomnia. METHODS We searched MEDLINE,… read more here.
Keywords: eszopiclone treatment; meta analysis; controlled trials; primary insomnia ... See more keywords
Suvorexant for the treatment of primary insomnia: A systematic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2017 at "Sleep medicine reviews"
DOI: 10.1016/j.smrv.2016.09.004
Abstract: Suvorexant is a dual orexin receptor agonist and is currently approved for the treatment of insomnia in the United States and Japan. We conducted a systematic review and meta-analysis to assess the efficacy and safety… read more here.
Keywords: primary insomnia; suvorexant treatment; insomnia; analysis ... See more keywords
Wendan decoction for primary insomnia
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DOI: 10.1097/md.0000000000008906
Abstract: Background: Insomnia is a widespread complaint in the general population. Wendan decoction has been widely applied in the treatment of primary insomnia. However, to our knowledge, there has been no systematic review or meta-analysis of… read more here.
Keywords: wendan decoction; medicine; primary insomnia; insomnia ... See more keywords
Electroacupuncture for primary insomnia
Sign Up to like & getrecommendations! Published in 2018 at "Medicine"
DOI: 10.1097/md.0000000000011063
Abstract: Background: Insomnia is a highly widespread sleep disorder in the general population. Electroacupuncture (EA) has been widely received attention as a potential treatment for primary insomnia. However, few previous studies are available to report that… read more here.
Keywords: primary insomnia; electroacupuncture; review; database ... See more keywords
Auriculotherapy for sleep quality in people with primary insomnia
Sign Up to like & getrecommendations! Published in 2019 at "Medicine"
DOI: 10.1097/md.0000000000014621
Abstract: Background: Primary insomnia is one of the common sleep disorders. Auriculotherapy originated from traditional Chinese medicine, has been thought as a promising treatment for primary insomnia. We aim to evaluate the efficacy and safety of… read more here.
Keywords: medicine; auriculotherapy; insomnia; primary insomnia ... See more keywords
Gene polymorphisms (rs324957, rs324981) in NPSR1 are associated with increased risk of primary insomnia
Sign Up to like & getrecommendations! Published in 2020 at "Medicine"
DOI: 10.1097/md.0000000000021598
Abstract: Abstract Neuropeptide S and neuropeptide S receptor (NPSR1) are associated with sleep regulation. Herein, the possible contribution of 6 polymorphisms in NPSR1 on the chromosome to primary insomnia (PI) and objective sleep phenotypes was investigated.… read more here.
Keywords: polymorphisms rs324957; gene polymorphisms; npsr1 associated; gene ... See more keywords
Declarative virtual water maze learning and emotional fear conditioning in primary insomnia
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Sleep Research"
DOI: 10.1111/jsr.12693
Abstract: Healthy sleep restores the brain's ability to adapt to novel input through memory formation based on activity‐dependent refinements of the strength of neural transmission across synapses (synaptic plasticity). In line with this framework, patients with… read more here.
Keywords: fear; water maze; primary insomnia; virtual water ... See more keywords
Disrupted white matter integrity in primary insomnia and major depressive disorder: relationships to sleep quality and depression severity.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of sleep research"
DOI: 10.1111/jsr.13913
Abstract: This study examined the integrity of white matter tracts in 25 participants with primary insomnia (PI), 50 participants with major depressive disorder (MDD), and 25 healthy controls. Seven white matter tracts, selected based on prior… read more here.
Keywords: matter; primary insomnia; white matter; depression severity ... See more keywords
Abnormal amplitude of low-frequency fluctuations associated with rapid-eye movement in chronic primary insomnia patients.
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DOI: 10.18632/oncotarget.17921
Abstract: PURPOSE Chronic primary insomnia (CPI) is the most prevalent sleep disorder worldwide. CPI manifests as difficulties in sleep onset, maintaining sleep, prolonged sleep latency, and daytime impairment and is often accompanied by cognitive problems such… read more here.
Keywords: insomnia patients; primary insomnia; chronic primary; rapid eye ... See more keywords