Screening of Hydrocarbon-Stapled Peptides for Inhibition of Calcium-Triggered Exocytosis
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DOI: 10.3389/fphar.2022.891041
Abstract: The so-called primary interface between the SNARE complex and synaptotagmin-1 (Syt1) is essential for Ca2+-triggered neurotransmitter release in neuronal synapses. The interacting residues of the primary interface are conserved across different species for synaptotagmins (Syt1,… read more here.
Keywords: stapled peptides; primary interface; ca2; hydrocarbon stapled ... See more keywords