Irritating effects of sodium lauryl sulfate on human primary keratinocytes at subtoxic levels of exposure
Sign Up to like & getrecommendations! Published in 2018 at "Microscopy Research and Technique"
DOI: 10.1002/jemt.23143
Abstract: Chemical agents that can potentially cause skin irritation are typically tested in animal models or in vitro assays of cell viability or cytokine expression. However, these methods do not always provide translatable results and are… read more here.
Keywords: primary keratinocytes; lauryl sulfate; microscopy; sodium lauryl ... See more keywords
Cytotoxic, genotoxic, and toxicogenomic effects of dihydroxyacetone in human primary keratinocytes
Sign Up to like & getrecommendations! Published in 2021 at "Cutaneous and Ocular Toxicology"
DOI: 10.1080/15569527.2021.1931877
Abstract: Abstract Purpose Dihydroxyacetone (DHA) is the only ingredient approved by the U.S. FDA as a colour additive in sunless tanning (self-tanning) products. Consumer sunless tanning products available for retail purchase contain 1–15% DHA. Although originally… read more here.
Keywords: primary keratinocytes; gene expression; expression changes; dha ... See more keywords
FoxO1 enhances differentiation and apoptosis in human primary keratinocytes
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Dermatology"
DOI: 10.1111/exd.13775
Abstract: Forkhead box‐O1 (FoxO1) is a key nutrient‐ and growth factor‐dependent regulator of metabolism, but its functional role in human primary keratinocytes (HPKs) is less known. To investigate the role of FoxO1 in HPKs and effect… read more here.
Keywords: primary keratinocytes; differentiation apoptosis; foxo1; expression ... See more keywords
Isolation and culture of human primary keratinocytes—a methods review
Sign Up to like & getrecommendations! Published in 2019 at "Experimental Dermatology"
DOI: 10.1111/exd.13860
Abstract: Keratinocyte culture is a necessary and widely used tool in a variety of experimental dermatological and biomedical studies. Literature search has revealed a variety of different protocols of human primary keratinocyte isolation and culture. Therefore,… read more here.
Keywords: primary keratinocytes; keratinocytes methods; isolation culture; culture human ... See more keywords
Interferon-Lambda 1 Inhibits Staphylococcus aureus Colonization in Human Primary Keratinocytes
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.652302
Abstract: Atopic dermatitis (AD) is a common inflammatory skin disease. Staphylococcus aureus (S. aureus) colonization in skin lesions occurs in approximately 70% of AD patients. It has been found that IFN-λ1 can inhibit the colonization of… read more here.
Keywords: staphylococcus aureus; primary keratinocytes; aureus colonization; colonization ... See more keywords