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   Articles with "primary membranous" as a keyword



Podocyte Pathogenic Bone Morphogenetic Protein‐2 Pathway and Immune Cell Behaviors in Primary Membranous Nephropathy

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recommendations! Published in 2024 at "Advanced Science"

DOI: 10.1002/advs.202404151

Abstract: Primary membranous nephropathy (PMN) is one of the leading causes of end‐stage renal disease, and the most frequent cause of massive proteinuria in nondiabetic adults, resulting in fatal complications. However, the underlying pathomechanisms of PMN… read more here.

Keywords: membranous nephropathy; podocyte pathogenic; cell; immune ... See more keywords
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Treatment of primary membranous nephropathy: where are we now?

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recommendations! Published in 2017 at "Journal of Nephrology"

DOI: 10.1007/s40620-017-0427-5

Abstract: In the last 10 years, basic science and clinical research have made important contributions to the understanding and management of primary membranous nephropathy (MN). The identification of antibodies directed against the M-type phospholipase A2 receptor (PLA2R)… read more here.

Keywords: nephrology; treatment primary; treatment; membranous nephropathy ... See more keywords
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A conceptual framework linking immunology, pathology, and clinical features in primary membranous nephropathy.

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recommendations! Published in 2021 at "Kidney international"

DOI: 10.1016/j.kint.2021.03.028

Abstract: Primary membranous nephropathy (PMN) is a leading cause of adult nephrotic syndrome. The field took a major step forward with the identification of phospholipase A2 receptor (PLA2R) as target antigen in the majority of cases… read more here.

Keywords: disease; pathology; membranous nephropathy; conceptual framework ... See more keywords

Clinical and pathologic features of primary membranous nephropathy in Turkey: a multicenter study by the Turkish Society of Nephrology Glomerular Diseases Working Group

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recommendations! Published in 2022 at "Renal Failure"

DOI: 10.1080/0886022x.2022.2079526

Abstract: Abstract Background We aimed to evaluate the features of primary membranous nephropathy (MNP) in Turkish people. Methods This is a retrospective analysis of patients with biopsy-proven primary MNP. We obtained the data collected between 2009… read more here.

Keywords: society nephrology; turkish society; features primary; membranous nephropathy ... See more keywords

The thickness of glomerular basement membrane predicts complete remission in primary membranous nephropathy

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recommendations! Published in 2023 at "Renal Failure"

DOI: 10.1080/0886022x.2023.2179335

Abstract: Abstract Objective: Glomerular basement membrane (GBM) thickening is a typical and essential histopathological characteristic for the diagnosis of primary membranous nephropathy (PMN). The present study aimed to explore the relationship between GBM thickness and treatment… read more here.

Keywords: glomerular basement; basement membrane; thickness; gbm thickness ... See more keywords

Establishing a differential diagnosis model between primary membranous nephropathy and non-primary membranous nephropathy by machine learning algorithms

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recommendations! Published in 2024 at "Renal Failure"

DOI: 10.1080/0886022x.2024.2380752

Abstract: Abstract Context Four algorithms with relatively balanced complexity and accuracy in deep learning classification algorithm were selected for differential diagnosis of primary membranous nephropathy (PMN). Objective This study explored the most suitable classification algorithm for… read more here.

Keywords: diagnosis; differential diagnosis; membranous nephropathy; pmn ... See more keywords

A multicenter retrospective study on comparing the efficacy and safety of the therapy of intermittent cyclophosphamide and corticosteroids versus rituximab for primary membranous nephropathy

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recommendations! Published in 2024 at "Renal Failure"

DOI: 10.1080/0886022x.2024.2409353

Abstract: Abstract Background Few clinical studies compare the long-term remission, relapse, and safety of rituximab (RTX) or a combination of intermittent intravenous infusion of cyclophosphamide (CTX) and oral corticosteroid for primary membranous nephropathy (PMN) patients. Methods… read more here.

Keywords: cyclophosphamide; membranous nephropathy; multicenter retrospective; remission ... See more keywords

A study on the association between serum antiphospholipase A2 receptor antibodies and the hypercoagulable state in Chinese patients with primary membranous nephropathy

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recommendations! Published in 2025 at "Renal Failure"

DOI: 10.1080/0886022x.2025.2581751

Abstract: Abstract Primary membranous nephropathy (PMN) increases venous thromboembolism (VTE) risk. This study investigated the relationship between anti-phospholipase A2 receptor (PLA2R) antibody status and coagulation profiles via thromboelastography (TEG) in PMN patients. In this retrospective study,… read more here.

Keywords: anti pla2r; membranous nephropathy; hypercoagulable state; study ... See more keywords

Comparison of 2 Anti-PLA2R Immunoassays for the Diagnosis of Primary Membranous Nephropathy

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recommendations! Published in 2018 at "Laboratory Medicine"

DOI: 10.1093/labmed/lmy016

Abstract: Background Anti-phospholipase A2 receptor (anti-PLA2R) is a promising biomarker for diagnosis, activity evaluation, therapy monitoring, and prognostic estimation of primary membranous neuropathy (pMN). Difference in methodology may be one cause of the discrepancy in anti-PLA2R-positive… read more here.

Keywords: primary membranous; anti pla2r; pla2r; iif elisa ... See more keywords
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MO321THE USE OF INTRAVENOUS CYCLOPHOSPHAMIDE AND ORAL STEROIDS IN PRIMARY MEMBRANOUS NEPHROPATHY WITH ADVANCED KIDNEY DISEASE

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recommendations! Published in 2021 at "Nephrology Dialysis Transplantation"

DOI: 10.1093/ndt/gfab104.0079

Abstract: International guidelines do not recommend specific use of immunosuppression treatment in membranous nephropathy patients presenting with an estimated glomerular filtration rate of read more here.

Keywords: immunosuppression; treatment; membranous nephropathy; nephropathy advanced ... See more keywords

#689 Obinutuzumab in patients with previously untreated primary membranous nephropathy

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recommendations! Published in 2024 at "Nephrology Dialysis Transplantation"

DOI: 10.1093/ndt/gfae069.438

Abstract: Primary membranous nephropathy (PMN) is the most common cause of nephrotic syndrome (NS) in adults and is currently considered an autoimmune-related disease. B cell depleting treatments, currently the most commonly used is rituximab, are usually… read more here.

Keywords: membranous nephropathy; obinutuzumab initial; remission; primary membranous ... See more keywords