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Published in 2017 at "Journal of Nephrology"
DOI: 10.1007/s40620-017-0427-5
Abstract: In the last 10 years, basic science and clinical research have made important contributions to the understanding and management of primary membranous nephropathy (MN). The identification of antibodies directed against the M-type phospholipase A2 receptor (PLA2R)… read more here.
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Published in 2021 at "Kidney international"
DOI: 10.1016/j.kint.2021.03.028
Abstract: Primary membranous nephropathy (PMN) is a leading cause of adult nephrotic syndrome. The field took a major step forward with the identification of phospholipase A2 receptor (PLA2R) as target antigen in the majority of cases… read more here.
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Published in 2022 at "Renal Failure"
DOI: 10.1080/0886022x.2022.2079526
Abstract: Abstract Background We aimed to evaluate the features of primary membranous nephropathy (MNP) in Turkish people. Methods This is a retrospective analysis of patients with biopsy-proven primary MNP. We obtained the data collected between 2009… read more here.
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Published in 2023 at "Renal Failure"
DOI: 10.1080/0886022x.2023.2179335
Abstract: Abstract Objective: Glomerular basement membrane (GBM) thickening is a typical and essential histopathological characteristic for the diagnosis of primary membranous nephropathy (PMN). The present study aimed to explore the relationship between GBM thickness and treatment… read more here.
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Published in 2018 at "Laboratory Medicine"
DOI: 10.1093/labmed/lmy016
Abstract: Background Anti-phospholipase A2 receptor (anti-PLA2R) is a promising biomarker for diagnosis, activity evaluation, therapy monitoring, and prognostic estimation of primary membranous neuropathy (pMN). Difference in methodology may be one cause of the discrepancy in anti-PLA2R-positive… read more here.
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Published in 2021 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfab104.0079
Abstract: International guidelines do not recommend specific use of immunosuppression treatment in membranous nephropathy patients presenting with an estimated glomerular filtration rate of read more here.
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Published in 2019 at "Postgraduate Medical Journal"
DOI: 10.1136/postgradmedj-2018-135729
Abstract: Membranous nephropathy (MN) is the most common cause of nephrotic syndrome in non-diabetic Caucasian adults over 40 years of age. It has an estimated incidence of 8–10 cases per 1 million. Fifty per cent of… read more here.
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Published in 2018 at "American Journal of Nephrology"
DOI: 10.1159/000488728
Abstract: Background: Currently, there is an urgent need to find ways of identifying primary membranous nephropathy (PMN) patients who are likely to benefit from calcineurin inhibitors (CNI) or who are resistant to them. In this study,… read more here.
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Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0217116
Abstract: Introduction Management of the Primary Membranous Nephropathy (PMN) usually involves administration of immunosuppressives. Cyclophosphamide (Cyclo) and Calcineurin Inhibitors (CNIs) are both widely used but only limited data exist to compare their efficacy in long term… read more here.
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Published in 2023 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s404591
Abstract: Background Primary membranous nephropathy (PMN) is a common cause of nephrotic syndrome in adults. Forty percent of the patients continue to progress and eventually develop into chronic renal failure. Although phospholipase A2 receptor (PLA2R) is… read more here.
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Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1009864
Abstract: Primary membranous nephropathy (MN) is an important cause of nephrotic syndrome and chronic kidney disease (CKD) in the adult population. Although the discovery of different autoantibodies against glomerular/podocytic antigens have highlighted the role of B… read more here.