Application of a Neural Network Whole Transcriptome–Based Pan-Cancer Method for Diagnosis of Primary and Metastatic Cancers
Sign Up to like & getrecommendations! Published in 2019 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2019.2597
Abstract: This cross-sectional diagnostic study evaluates the accuracy of a machine learning method that uses the whole transcriptome to identify gene markers in primary and metastatic tumors. read more here.
Keywords: whole transcriptome; network whole; primary metastatic; neural network ... See more keywords
Identification of differentially expressed genes and functional annotations associated with metastases of the uveal melanoma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29250
Abstract: Uveal melanoma (UVM) is an adult intraocular malignancy which is the most frequent and has a high tendency for metastasis. This study aims to develop significant differential gene subnetwork between primary and metastatic UVM to… read more here.
Keywords: functional annotations; metastatic uvm; uveal melanoma; primary metastatic ... See more keywords
Exosomes Derived from Human Primary and Metastatic Colorectal Cancer Cells Contribute to Functional Heterogeneity of Activated Fibroblasts by Reprogramming Their Proteome
Sign Up to like & getrecommendations! Published in 2019 at "PROTEOMICS"
DOI: 10.1002/pmic.201800148
Abstract: Cancer‐associated fibroblasts (CAFs) are a heterogeneous population of activated fibroblasts that constitute a dominant cellular component of the tumor microenvironment (TME) performing distinct functions. Here, the role of tumor‐derived exosomes (Exos) in activating quiescent fibroblasts… read more here.
Keywords: activated fibroblasts; colorectal cancer; exosomes derived; primary metastatic ... See more keywords
Cu2 MoS4 /Au Heterostructures with Enhanced Catalase-Like Activity and Photoconversion Efficiency for Primary/Metastatic Tumors Eradication by Phototherapy-Induced Immunotherapy.
Sign Up to like & getrecommendations! Published in 2020 at "Small"
DOI: 10.1002/smll.201907146
Abstract: Photoimmunotherapy can not only effectively ablate the primary tumor but also trigger strong antitumor immune responses against metastatic tumors by inducing immunogenic cell death. Herein, Cu2 MoS4 (CMS)/Au heterostructures are constructed by depositing plasmonic Au… read more here.
Keywords: tumors eradication; cms; primary metastatic; phototherapy induced ... See more keywords
Leiomyoma and Leiomyosarcoma (Primary and Metastatic) of the Oral and Maxillofacial Region: A Clinicopathological and Immunohistochemical Study of 27 Cases
Sign Up to like & getrecommendations! Published in 2021 at "Head and Neck Pathology"
DOI: 10.1007/s12105-021-01336-2
Abstract: Smooth muscle neoplasms represent an important group of lesions which is rare in the oral cavity. Leiomyoma (LM) is benign smooth muscle/pericytic tumor usually presenting as non-aggressive neoplasm, while leiomyosarcoma (LMS) represents its malignant counterpart.… read more here.
Keywords: oral maxillofacial; leiomyoma leiomyosarcoma; pathology; primary metastatic ... See more keywords
Discordance of PD-L1 status between primary and metastatic breast cancer: A systematic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer treatment reviews"
DOI: 10.1016/j.ctrv.2021.102257
Abstract: INTRODUCTION Programmed cell death ligand 1 (PD-L1) expression is predictive for benefit from immunotherapy in several human malignancies including triple negative breast cancer. Lower positivity rates but a larger relative benefit from atezolizumab has been… read more here.
Keywords: discordance; breast cancer; primary metastatic; metastatic breast ... See more keywords
Primary metastatic breast cancer in the era of targeted therapy - Prognostic impact and the role of breast tumour surgery.
Sign Up to like & getrecommendations! Published in 2017 at "European journal of cancer"
DOI: 10.1016/j.ejca.2017.06.002
Abstract: BACKGROUND Except for meeting the individual palliative need, the benefit of breast surgery in primary metastatic breast cancer (PMBC), also known as de novo metastatic breast cancer, on long-term outcomes remains controversial. Twenty-four hundred and… read more here.
Keywords: surgery; breast; breast cancer; primary metastatic ... See more keywords
Recurrent genetic alterations and biomarker expression in primary and metastatic squamous cell carcinomas of the vulva.
Sign Up to like & getrecommendations! Published in 2019 at "Human pathology"
DOI: 10.1016/j.humpath.2019.08.003
Abstract: Using a comprehensive next-generation sequencing pipeline (143 genes), Oncomine Comprehensive v.2, we analyzed genetic alterations on a set of vulvar squamous cell carcinomas (SCCs) with emphasis on the primary and metastatic samples from the same… read more here.
Keywords: squamous cell; primary metastatic; genetic alterations; expression ... See more keywords
Importance of Spinal Alignment in Primary and Metastatic Spine Tumors.
Sign Up to like & getrecommendations! Published in 2019 at "World neurosurgery"
DOI: 10.1016/j.wneu.2019.08.161
Abstract: Spinal alignment, particularly with respect to spinopelvic parameters, is highly correlated with morbidity and health-related quality-of-life outcomes. Although the importance of spinal alignment has been emphasized in the deformity literature, spinopelvic parameters have not been… read more here.
Keywords: alignment; importance spinal; primary metastatic; spinal alignment ... See more keywords
Risk Factors for Wound-Related Complications Following Surgery for Primary and Metastatic Spine Tumors: A Systematic Review and Meta-Analysis.
Sign Up to like & getrecommendations! Published in 2020 at "World neurosurgery"
DOI: 10.1016/j.wneu.2020.03.210
Abstract: OBJECTIVE We systematically reviewed the literature to compare risk factors for postoperative complications at the surgical wound site in primary and metastatic tumor operations. METHODS We screened English-language publications on the outcomes of primary and… read more here.
Keywords: risk; meta analysis; analysis; risk factors ... See more keywords
Concordance study of PD-L1 expression in primary and metastatic bladder carcinomas: comparison of four commonly used antibodies and RNA expression
Sign Up to like & getrecommendations! Published in 2017 at "Modern Pathology"
DOI: 10.1038/modpathol.2017.188
Abstract: Therapy with anti-PD-L1 immune check-point inhibitors is approved for several cancers, including advanced urothelial carcinomas. PD-L1 prevalence estimates vary widely in bladder cancer, and lack of correlation between expression and clinical outcomes and immunotherapy response… read more here.
Keywords: concordance; urothelial carcinomas; commonly used; primary metastatic ... See more keywords