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   Articles with "primary metastatic" as a keyword



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Application of a Neural Network Whole Transcriptome–Based Pan-Cancer Method for Diagnosis of Primary and Metastatic Cancers

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recommendations! Published in 2019 at "JAMA Network Open"

DOI: 10.1001/jamanetworkopen.2019.2597

Abstract: This cross-sectional diagnostic study evaluates the accuracy of a machine learning method that uses the whole transcriptome to identify gene markers in primary and metastatic tumors. read more here.

Keywords: whole transcriptome; network whole; primary metastatic; neural network ... See more keywords

Practical guidance for direct oral anticoagulant use in the treatment of venous thromboembolism in primary and metastatic brain tumor patients

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recommendations! Published in 2024 at "Cancer"

DOI: 10.1002/cncr.35220

Abstract: Management of venous thromboembolism (VTE) in patients with primary and metastatic brain tumors (BT) is challenging because of the risk of intracranial hemorrhage (ICH). There are no prospective clinical trials evaluating safety and efficacy of… read more here.

Keywords: brain; primary metastatic; metastatic brain; venous thromboembolism ... See more keywords
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Identification of differentially expressed genes and functional annotations associated with metastases of the uveal melanoma

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recommendations! Published in 2019 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.29250

Abstract: Uveal melanoma (UVM) is an adult intraocular malignancy which is the most frequent and has a high tendency for metastasis. This study aims to develop significant differential gene subnetwork between primary and metastatic UVM to… read more here.

Keywords: functional annotations; metastatic uvm; uveal melanoma; primary metastatic ... See more keywords

Exosomes Derived from Human Primary and Metastatic Colorectal Cancer Cells Contribute to Functional Heterogeneity of Activated Fibroblasts by Reprogramming Their Proteome

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recommendations! Published in 2019 at "PROTEOMICS"

DOI: 10.1002/pmic.201800148

Abstract: Cancer‐associated fibroblasts (CAFs) are a heterogeneous population of activated fibroblasts that constitute a dominant cellular component of the tumor microenvironment (TME) performing distinct functions. Here, the role of tumor‐derived exosomes (Exos) in activating quiescent fibroblasts… read more here.

Keywords: activated fibroblasts; colorectal cancer; exosomes derived; primary metastatic ... See more keywords

Cu2 MoS4 /Au Heterostructures with Enhanced Catalase-Like Activity and Photoconversion Efficiency for Primary/Metastatic Tumors Eradication by Phototherapy-Induced Immunotherapy.

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recommendations! Published in 2020 at "Small"

DOI: 10.1002/smll.201907146

Abstract: Photoimmunotherapy can not only effectively ablate the primary tumor but also trigger strong antitumor immune responses against metastatic tumors by inducing immunogenic cell death. Herein, Cu2 MoS4 (CMS)/Au heterostructures are constructed by depositing plasmonic Au… read more here.

Keywords: tumors eradication; cms; primary metastatic; phototherapy induced ... See more keywords

Effective Amplification of Oxidative Stress and Calcium Manipulation Mediated Mitochondrial Dysfunction Based on Engineered Nanozyme for Primary and Metastatic Breast Cancer Therapy.

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recommendations! Published in 2025 at "Small"

DOI: 10.1002/smll.202411299

Abstract: Herein, an engineered nanocomposite (FZSHC) was constructed containing zinc-based nanozyme(ZS), Hemin and Ca2+ ions with further surface modification of phospholipid and folic acid (FA) for primary and metastatic breast cancer therapy. During therapy, the FZSHC… read more here.

Keywords: breast cancer; therapy; primary metastatic; metastatic breast ... See more keywords

Leiomyoma and Leiomyosarcoma (Primary and Metastatic) of the Oral and Maxillofacial Region: A Clinicopathological and Immunohistochemical Study of 27 Cases

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recommendations! Published in 2021 at "Head and Neck Pathology"

DOI: 10.1007/s12105-021-01336-2

Abstract: Smooth muscle neoplasms represent an important group of lesions which is rare in the oral cavity. Leiomyoma (LM) is benign smooth muscle/pericytic tumor usually presenting as non-aggressive neoplasm, while leiomyosarcoma (LMS) represents its malignant counterpart.… read more here.

Keywords: oral maxillofacial; leiomyoma leiomyosarcoma; pathology; primary metastatic ... See more keywords
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Discordance of PD-L1 status between primary and metastatic breast cancer: A systematic review and meta-analysis.

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recommendations! Published in 2021 at "Cancer treatment reviews"

DOI: 10.1016/j.ctrv.2021.102257

Abstract: INTRODUCTION Programmed cell death ligand 1 (PD-L1) expression is predictive for benefit from immunotherapy in several human malignancies including triple negative breast cancer. Lower positivity rates but a larger relative benefit from atezolizumab has been… read more here.

Keywords: discordance; breast cancer; primary metastatic; metastatic breast ... See more keywords

Primary metastatic breast cancer in the era of targeted therapy - Prognostic impact and the role of breast tumour surgery.

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recommendations! Published in 2017 at "European journal of cancer"

DOI: 10.1016/j.ejca.2017.06.002

Abstract: BACKGROUND Except for meeting the individual palliative need, the benefit of breast surgery in primary metastatic breast cancer (PMBC), also known as de novo metastatic breast cancer, on long-term outcomes remains controversial. Twenty-four hundred and… read more here.

Keywords: surgery; breast; breast cancer; primary metastatic ... See more keywords

Recurrent genetic alterations and biomarker expression in primary and metastatic squamous cell carcinomas of the vulva.

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recommendations! Published in 2019 at "Human pathology"

DOI: 10.1016/j.humpath.2019.08.003

Abstract: Using a comprehensive next-generation sequencing pipeline (143 genes), Oncomine Comprehensive v.2, we analyzed genetic alterations on a set of vulvar squamous cell carcinomas (SCCs) with emphasis on the primary and metastatic samples from the same… read more here.

Keywords: squamous cell; primary metastatic; genetic alterations; expression ... See more keywords

Importance of Spinal Alignment in Primary and Metastatic Spine Tumors.

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recommendations! Published in 2019 at "World neurosurgery"

DOI: 10.1016/j.wneu.2019.08.161

Abstract: Spinal alignment, particularly with respect to spinopelvic parameters, is highly correlated with morbidity and health-related quality-of-life outcomes. Although the importance of spinal alignment has been emphasized in the deformity literature, spinopelvic parameters have not been… read more here.

Keywords: alignment; importance spinal; primary metastatic; spinal alignment ... See more keywords