SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes
Sign Up to like & getrecommendations! Published in 2021 at "Cell Death Discovery"
DOI: 10.1038/s41420-021-00428-w
Abstract: Infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been associated with leukopenia and uncontrolled inflammatory response in critically ill patients. A better comprehension of SARS-CoV-2-induced monocyte death is essential for the identification… read more here.
Keywords: cov engages; engages inflammasome; primary monocytes; human primary ... See more keywords
Capturing 3D Chromatin Maps of Human Primary Monocytes: Insights From High-Resolution Hi-C
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.837336
Abstract: Although the variation in chromatin architecture during adaptive immune responses has been thoroughly investigated, the 3D landscape of innate immunity is still unknown. Herein, chromatin regulation and heterogeneity among human primary monocytes were investigated. Peripheral… read more here.
Keywords: capturing chromatin; high resolution; resolution; chromatin ... See more keywords
A Heterotypic Tridimensional Model to Study the Interaction of Macrophages and Glioblastoma In Vitro
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DOI: 10.3390/ijms22105105
Abstract: Background: Glioblastoma multiforme (GBM) is the most frequent and aggressive primary brain tumor, and macrophages account for 30–40% of its composition. Most of these macrophages derive from bone marrow monocytes playing a crucial role in… read more here.
Keywords: model study; model; primary monocytes; monocytes thp ... See more keywords