NLRP3-directed antisense oligonucleotides reduce microglial immunoactivities in vitro.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of neurochemistry"
DOI: 10.1111/jnc.15778
Abstract: Alzheimer's disease (AD) is associated with the cerebral deposition of Amyloid-β (Aβ) peptide, which leads to NLRP3 inflammasome activation and subsequent release of interleukin-1β (IL-1β) and interleukin-18 (IL-18). NLRP3 reduction has been found to increase… read more here.
Keywords: nlrp3 directed; directed antisense; antisense oligonucleotides; primary murine ... See more keywords
The use of primary murine fibroblasts to ascertain if Spirocerca lupi secretory/excretory protein products are mitogenic ex vivo
Sign Up to like & getrecommendations! Published in 2017 at "BMC Veterinary Research"
DOI: 10.1186/s12917-017-1162-9
Abstract: BackgroundSpirocerca lupi is a nematode that parasitizes vertebrates in particular canids, by forming nodules in the thoracic cavity specifically in the oesophagus. In 25% of Spirocerca infections of the domestic dog, nodules progress from inflammatory… read more here.
Keywords: protein; murine; secretory excretory; murine fibroblasts ... See more keywords
A simplified procedure for isolation of primary murine microglia
Sign Up to like & getrecommendations! Published in 2022 at "Biotechniques"
DOI: 10.2144/btn-2022-0054
Abstract: There are various approaches in which one can isolate microglia from murine brains, such as immunomagnetic, density gradient, FACS and differential adhesive methods. In this procedure a modified flask-tapping approach was used due to its… read more here.
Keywords: cell; murine microglia; isolation primary; procedure isolation ... See more keywords
Influence of PEG Chain Length of Functionalized Magnetic Nanoparticles on the Cytocompatibility and Immune Competence of Primary Murine Macrophages and Dendritic Cells
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032565
Abstract: A major drawback of nanoparticles (NPs) for biomedical applications is their preferential phagocytosis in immune cells, which can be avoided by surface modifications like PEGylation. Nevertheless, examinations of different polyethylene glycol (PEG) chain lengths on… read more here.
Keywords: immune competence; competence; murine macrophages; peg chain ... See more keywords
Neuropathogenic and non-neuropathogenic EHV-1 strains induce the accumulation of hyperphosphorylated Tau in primary murine neurons.
Sign Up to like & getrecommendations! Published in 2020 at "Acta virologica"
DOI: 10.4149/av_2020_407
Abstract: Equid herpesvirus 1 (EHV-1) causes respiratory disease, abortion and neurological disorders in horses. Similarly, to other alphaherpesviruses, EHV-1 is neurotropic and establishes latency in the neurons of its natural host. Despite the fact that many… read more here.
Keywords: tau; accumulation hyperphosphorylated; ehv; primary murine ... See more keywords