Drosophila Primary Neuronal Cultures as a Useful Cellular Model to Study and Image Axonal Transport.
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DOI: 10.1007/978-1-0716-1990-2_23
Abstract: The use of primary neuronal cultures generated from Drosophila tissue provides a powerful model for studies of transport mechanisms. Cultured fly neurons provide similarly detailed subcellular resolution and applicability of pharmacology or fluorescent dyes as… read more here.
Keywords: transport; neuronal cultures; drosophila primary; model ... See more keywords
Isolation and Nanoscale Electroporation of Primary Neuronal Cultures In Situ.
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DOI: 10.1007/978-1-4939-9740-4_15
Abstract: Developing effective gene therapies for disorders of the central nervous system (CNS) is extremely challenging due to the lack of safe and efficient gene delivery methods to neurons and glial cells, hampering the study of… read more here.
Keywords: isolation nanoscale; neuronal cultures; nanoscale electroporation; electroporation ... See more keywords
Systematic Quantification of Synapses in Primary Neuronal Culture
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DOI: 10.1016/j.isci.2020.101542
Abstract: Summary Most neurological disorders display impaired synaptic connectivity. Hence, modulation of synapse formation may have therapeutic relevance. However, the high density and small size of synapses complicate their quantification. To improve synapse-oriented screens, we analyzed… read more here.
Keywords: synapse; systematic quantification; synapses primary; primary neuronal ... See more keywords