Direct Measurements of Primary Nucleation Rates of p-Aminobenzoic Acid and Glutamic Acid and Comparison with Predictions from Induction Time Distributions
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DOI: 10.1021/acs.iecr.8b03625
Abstract: The model-based estimation of primary nucleation rates from the probability distribution of induction time measurements has been used extensively in the literature; however, there has been no experimental validation of this approach via direct measurements… read more here.
Keywords: nucleation; induction time; nucleation rates; primary nucleation ... See more keywords
Primary Nucleation of Benzoic Acid in Aqueous Ethanol Solution
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DOI: 10.1021/acs.iecr.9b05640
Abstract: The knowledge of crystallization kinetics, especially crystal nucleation, is crucial for crystallization process design and control. In the present paper, the primary nucleation kinetics of benzoic acid in water-ethanol solution were estimated from induction time… read more here.
Keywords: energy; water; ethanol solution; nucleation ... See more keywords
Chaperones mainly suppress primary nucleation during formation of functional amyloid required for bacterial biofilm formation
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DOI: 10.1039/d1sc05790a
Abstract: Unlike misfolding in neurodegenerative diseases, aggregation of functional amyloids involved in bacterial biofilm, e.g. CsgA (E. coli) and FapC (Pseudomonas), is carefully regulated. However, it is unclear whether functional aggregation is inhibited by chaperones targeting… read more here.
Keywords: bacterial biofilm; primary nucleation; nucleation; fapc ... See more keywords
Amyloid formation of fish β-parvalbumin involves primary nucleation triggered by disulfide-bridged protein dimers
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DOI: 10.1073/pnas.2015503117
Abstract: Significance Amyloid fibrils are generally related to neurodegenerative diseases, but they can also be part of normal protein function. Amyloid formation involves numerous steps and intermediate species. In this study, we investigated a fish protein,… read more here.
Keywords: protein; aggregation; formation; primary nucleation ... See more keywords