The gene mutational discrepancies between primary and paired metastatic colorectal carcinoma detected by next-generation sequencing
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DOI: 10.1007/s00432-018-2742-1
Abstract: PurposeTo better understand the gene mutational status and heterogeneity between primary and metastatic CRC (mCRC) using a sensitive sequencing method.MethodsThe mutational status of EGFR, KRAS, NRAS, PIK3CA, ERBB2, BRAF, KIT, and PDGFRA was analyzed in… read more here.
Keywords: gene mutational; primary paired; mutational status; gene ... See more keywords