Uncovering the invisible—prevalence, characteristics, and radiomics feature–based detection of visually undetectable intraprostatic tumor lesions in 68GaPSMA-11 PET images of patients with primary prostate cancer
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-020-05111-3
Abstract: Primary prostate cancer (PCa) can be visualized on prostate-specific membrane antigen positron emission tomography (PSMA-PET) with high accuracy. However, intraprostatic lesions may be missed by visual PSMA-PET interpretation. In this work, we quantified and characterized… read more here.
Keywords: primary prostate; interpretation; prostate cancer; psma pet ... See more keywords
Immortalization of human primary prostate epithelial cells via CRISPR inactivation of the CDKN2A locus and expression of telomerase
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DOI: 10.1038/s41391-020-00274-4
Abstract: Background Immortalization of primary prostate epithelial cells (PrEC) with just hTERT expression is particularly inefficient in the absence of DNA tumor viral proteins or p16 INK4A knockdown. Materials and methods Here, we describe the establishment… read more here.
Keywords: prostate; primary prostate; cell; expression ... See more keywords
MP62-16 A PROSPECTIVE EVALUATION OF PELVIC LYMPH NODE STAGING WITH 18 FLUORINE PROSTATE-SPECIFIC MEMBRANE ANTIGEN PET/CT PRIOR TO EXTENDED LYMPH NODE DISSECTION IN PRIMARY PROSTATE CANCER. THE SALT STUDY
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Urology"
DOI: 10.1097/ju.0000000000000937.016
Abstract: INTRODUCTION AND OBJECTIVE:Accurate detection of pelvic lymph node metastases (N-stage) in patients with primary prostate cancer (PCa) is important for disease prognostics, therapeutic decisions, a... read more here.
Keywords: lymph node; pelvic lymph; prostate; primary prostate ... See more keywords
Abstract 6081: Integrative genomic analysis of primary prostate tumors and corresponding lymph node metastases
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DOI: 10.1158/1538-7445.am2023-6081
Abstract: Background: Prostate cancer (PCa) is a highly heterogeneous disease, and mortality is mainly due to metastases. However, the molecular underpinnings that lead to the initial steps of metastasis have not been well characterized. We have… read more here.
Keywords: node metastases; analysis primary; corresponding lymph; analysis ... See more keywords
Performance of 68Ga-labeled prostate-specific membrane antigen ligand positron emission tomography/computed tomography in the diagnosis of primary prostate cancer: a systematic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2021 at "International braz j urol : official journal of the Brazilian Society of Urology"
DOI: 10.1590/s1677-5538.ibju.2020.0986
Abstract: OBJECTIVE To explore the feasibility of 68Ga-PSMA PET/CT in diagnosing primary prostate cancer. MATERIALS AND METHODS Embase, PubMed and Cochrane Library databases were searched for studies published before July 2020. The studies that used 68Ga-PSMA… read more here.
Keywords: 68ga psma; prostate; primary prostate; psma pet ... See more keywords
Critical evaluation of the subcutaneous engraftments of hormone naïve primary prostate cancer.
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DOI: 10.21037/tau.2020.03.38
Abstract: Background Patient-derived xenografts (PDXs) are considered to better recapitulate the histopathological and molecular heterogeneity of human cancer than other preclinical models. Despite technological advances, PDX models from hormone naïve primary prostate cancer are scarce. We… read more here.
Keywords: prostate; primary prostate; cancer; hormone primary ... See more keywords