Articles with "primary screens" as a keyword



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CLAffinity: A Software Tool for Identification of Optimum Ligand Affinity for Competition-Based Primary Screens

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Published in 2022 at "Journal of Chemical Information and Modeling"

DOI: 10.1021/acs.jcim.2c00285

Abstract: A simplistic assumption in setting up a competition assay is that a low affinity labeled ligand can be more easily displaced from a target protein than a high affinity ligand, which in turn produces a… read more here.

Keywords: competition based; primary screens; affinity; ligand ... See more keywords