N6‐Methyladenosine Demethylase FTO Contributes to Neuropathic Pain by Stabilizing G9a Expression in Primary Sensory Neurons
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Science"
DOI: 10.1002/advs.201902402
Abstract: Abstract Nerve injury‐induced change in gene expression in primary sensory neurons of dorsal root ganglion (DRG) is critical for neuropathic pain genesis. N6‐methyladenosine (m6A) modification of RNA represents an additional layer of gene regulation. Here,… read more here.
Keywords: sensory neurons; neuropathic pain; nerve injury; primary sensory ... See more keywords
Usefulness of the measurement of neurite outgrowth of primary sensory neurons to study cancer-related painful complications.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2021.114520
Abstract: Abnormal outgrowth of sensory nerves is one of the important contributors to pain associated with cancer and its treatments. Primary neuronal cultures derived from dorsal root ganglia (DRG) have been widely used to study pain-associated… read more here.
Keywords: cancer related; neurite outgrowth; sensory neurons; cancer ... See more keywords
Primary sensory neurons expressing tropomyosin receptor kinase A in the rat trigeminal ganglion
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2018.10.009
Abstract: Tropomyosin receptor kinase A (trkA), a high affinity receptor for nerve growth factor (NGF), has been implicated in neuronal survival, neurite outgrowth and inflammatory pain. So far, the characterization of the primary sensory neurons that… read more here.
Keywords: receptor kinase; tropomyosin receptor; sensory neurons; receptor ... See more keywords
Dorsal Root Ganglia Homeobox downregulation in primary sensory neurons contributes to neuropathic pain in rats
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DOI: 10.1177/1744806920904462
Abstract: Transcriptional changes in primary sensory neurons are involved in initiation and maintenance of neuropathic pain. However, the transcription factors in primary sensory neurons responsible for neuropathic pain are not fully understood. Dorsal Root Ganglia Homeobox… read more here.
Keywords: sensory neurons; downregulation; neuropathic pain; primary sensory ... See more keywords