Npom‐Protected NONOate Enables Light‐Triggered NO/cGMP Signalling in Primary Vascular Smooth Muscle Cells
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DOI: 10.1002/cbic.201700683
Abstract: Diazeniumdiolates (NONOates) are a class of nitric‐oxide‐releasing substances widely used in studies of NO/cGMP signalling. Because spatiotemporal control is highly desirable for such purposes, we have synthesised a new Npom‐caged pyrrolidine NONOate. A kinetic analysis… read more here.
Keywords: vascular smooth; cgmp signalling; muscle cells; npom protected ... See more keywords
Hydrophobe-substituted bPEI derivatives: boosting transfection on primary vascular cells
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DOI: 10.1007/s40843-017-9030-7
Abstract: Gene therapy targeted to vascular cells represents a promising approach for prevention and treatment of pathological conditions such as intimal hyperplasia, in-stent and post-angioplasty restenosis. In this context, polymeric non-viral gene delivery systems are a… read more here.
Keywords: bpei derivatives; vascular cells; transfection; primary vascular ... See more keywords
Early ontogeny defines the diversification of primary vascular bundle systems in angiosperms
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DOI: 10.1093/botlinnean/boaa084
Abstract: Understanding vascular bundle systems in angiosperms is a challenge. On the one hand, the vascular tissue is extremely important in reconstructing the evolution and survivability of plants, but on the other hand, it forms a… read more here.
Keywords: bundle formation; bundle systems; vascular bundle; systems angiosperms ... See more keywords
STING inhibition enables efficient plasmid-based gene expression in primary vascular cells: A simple and cost-effective transfection protocol
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DOI: 10.1371/journal.pone.0303472
Abstract: Plasmid transfection in cells is widely employed to express exogenous proteins, offering valuable mechanistic insight into their function(s). However, plasmid transfection efficiency in primary vascular endothelial cells (ECs) and smooth muscle cells (SMCs) is restricted… read more here.
Keywords: primary vascular; gene expression; transfection; efficient plasmid ... See more keywords