A single-nucleus transcriptomic atlas of primate testicular aging reveals exhaustion of the spermatogonial stem cell reservoir and loss of Sertoli cell homeostasis.
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DOI: 10.1093/procel/pwac057
Abstract: The testis is pivotal for male reproduction, and its progressive functional decline in aging is associated with infertility. However, the regulatory mechanism underlying primate testicular aging remains largely elusive. Here, we resolve the aging-related cellular… read more here.
Keywords: cell; single nucleus; primate testicular; nucleus transcriptomic ... See more keywords