Articles with "prime boost" as a keyword



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Longitudinal study comparing IgG antibodies induced by heterologous prime‐boost COVID‐19 vaccine

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Published in 2022 at "Journal of Medical Virology"

DOI: 10.1002/jmv.28379

Abstract: Vaccines are critical cost‐effective tools to control the COVID‐19 pandemic. The heterologous prime‐boost vaccination has been used by many countries to overcome supply issues, so the effectiveness and safety of this strategy need to be… read more here.

Keywords: boost covid; heterologous prime; prime boost; vaccine ... See more keywords
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Heterologous prime-boost immunization with vesiculovirus-based vectors expressing HBV Core antigen induces CD8+ T cell responses in naïve and persistently infected mice and protects from challenge.

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Published in 2019 at "Antiviral research"

DOI: 10.1016/j.antiviral.2019.05.014

Abstract: Chronic hepatitis B virus (HBV) infections cause more than 800,000 deaths per year and currently approved treatments do not cure the disease. Because a hallmark of acute infection resolution is the presence of functional CD8+… read more here.

Keywords: prime boost; hbv; boost immunization; core ... See more keywords
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Comparison of homologous and heterologous prime-boost immunizations combining MVA-vectored and plant-derived VP2 as a strategy against IBDV.

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Published in 2017 at "Vaccine"

DOI: 10.1016/j.vaccine.2016.11.029

Abstract: Different immunogens such as subunit, DNA or live viral-vectored vaccines against Infectious Bursal Disease virus (IBDV) have been evaluated in the last years. However, the heterologous prime-boost approach using recombinant modified vaccinia Ankara virus (rMVA),… read more here.

Keywords: heterologous prime; ibdv; immune response; prime boost ... See more keywords
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Safety and immunogenicity of an 8 year interval heterologous prime-boost influenza A/H7N7-H7N9 vaccination.

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Published in 2019 at "Vaccine"

DOI: 10.1016/j.vaccine.2019.03.071

Abstract: BACKGROUND Influenza A/H7N9 viruses are undergoing antigenic drift since their emergence in 2013, and vaccination strategies are needed for pandemic preparedness. Two doses of adjuvanted monovalent inactivated influenza A/H7N9 vaccine (IIV1 A/H7N9) are needed for… read more here.

Keywords: h7n9; iiv1 h7n9; influenza h7n9; prime boost ... See more keywords
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Positive immunomodulatory effects of heterologous DNA vaccine- modified live vaccine, prime-boost immunization, against the highly-pathogenic PRRSV infection.

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Published in 2017 at "Veterinary immunology and immunopathology"

DOI: 10.1016/j.vetimm.2016.11.002

Abstract: Porcine reproductive and respiratory syndrome virus (PRRSV) infection is one of the most important swine pathogens, and causes a major economic impact worldwide. Recently, a new variant type 2 PRRSV, highly pathogenic PRRSV (HP-PRRSV) has… read more here.

Keywords: dna; prime boost; prrsv infection; vaccine ... See more keywords
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Heterologous Prime-Boost Enhances the Antitumor Immune Response Elicited by Plant-Virus-Based Cancer Vaccine.

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Published in 2019 at "Journal of the American Chemical Society"

DOI: 10.1021/jacs.9b01523

Abstract: New cancer vaccine strategies are required to vanquish the self-tolerance and elicit robust immune responses against tumor-associated antigens and/or neoantigens. Contemporary approaches in nanomedicine center on the use of a single nanocarrier modified with multiple… read more here.

Keywords: response; prime boost; based cancer; cancer vaccine ... See more keywords
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Heterologous prime-boost with A(H5N1) pandemic influenza vaccines induces broader cross-clade antibody responses than homologous prime-boost

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Published in 2019 at "NPJ Vaccines"

DOI: 10.1038/s41541-019-0114-8

Abstract: Highly pathogenic avian influenza (HPAI) A(H5Nx) viruses continue to pose a pandemic threat. US national vaccine stockpiles are a cornerstone of the influenza pandemic preparedness plans. However, continual genetic and antigenic divergence of A(H5Nx) viruses… read more here.

Keywords: prime boost; boost; antibody; clade ... See more keywords
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Single-administration, thermostable human papillomavirus vaccines prepared with atomic layer deposition technology

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Published in 2020 at "NPJ Vaccines"

DOI: 10.1038/s41541-020-0195-4

Abstract: Cold-chain requirements affect worldwide distribution of many vaccines. In addition, vaccines requiring multiple doses impose logistical and financial burdens, as well as patient compliance barriers. To address such limitations, we have developed new technologies to… read more here.

Keywords: atomic layer; layer deposition; antigen; prime boost ... See more keywords
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Antitumour dendritic cell vaccination in a priming and boosting approach

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Published in 2020 at "Nature Reviews Drug Discovery"

DOI: 10.1038/s41573-020-0074-8

Abstract: Mobilizing antitumour immunity through vaccination potentially constitutes a powerful anticancer strategy but has not yet provided robust clinical benefits in large patient populations. Although major hurdles still exist, we believe that currently available strategies for… read more here.

Keywords: prime boost; approach; vaccination; cell ... See more keywords
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Intranasal plus subcutaneous prime vaccination with a dual antigen COVID-19 vaccine elicits T-cell and antibody responses in mice

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Published in 2021 at "Scientific Reports"

DOI: 10.1038/s41598-021-94364-5

Abstract: We have developed a COVID-19 vaccine, hAd5 S-Fusion + N-ETSD, that expresses SARS-CoV-2 spike (S) and nucleocapsid (N) proteins with modifications to increase immune responses delivered using a human adenovirus serotype 5 (hAd5) platform. Here, we demonstrate… read more here.

Keywords: subcutaneous prime; prime boost; covid vaccine; vaccination ... See more keywords
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A Bivalent Heterologous DNA Virus-Like-Particle Prime-Boost Vaccine Elicits Broad Protection against both Group 1 and 2 Influenza A Viruses

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Published in 2017 at "Journal of Virology"

DOI: 10.1128/jvi.02052-16

Abstract: ABSTRACT Current seasonal influenza vaccines are efficacious when vaccine strains are matched with circulating strains. However, they do not protect antigenic variants and newly emerging pandemic and outbreak strains. Thus, there is a critical need… read more here.

Keywords: prime boost; influenza; group; vaccine ... See more keywords