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Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28379
Abstract: Vaccines are critical cost‐effective tools to control the COVID‐19 pandemic. The heterologous prime‐boost vaccination has been used by many countries to overcome supply issues, so the effectiveness and safety of this strategy need to be…
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Keywords:
boost covid;
heterologous prime;
prime boost;
vaccine ... See more keywords
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Published in 2019 at "Antiviral research"
DOI: 10.1016/j.antiviral.2019.05.014
Abstract: Chronic hepatitis B virus (HBV) infections cause more than 800,000 deaths per year and currently approved treatments do not cure the disease. Because a hallmark of acute infection resolution is the presence of functional CD8+…
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Keywords:
prime boost;
hbv;
boost immunization;
core ... See more keywords
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Published in 2017 at "Vaccine"
DOI: 10.1016/j.vaccine.2016.11.029
Abstract: Different immunogens such as subunit, DNA or live viral-vectored vaccines against Infectious Bursal Disease virus (IBDV) have been evaluated in the last years. However, the heterologous prime-boost approach using recombinant modified vaccinia Ankara virus (rMVA),…
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Keywords:
heterologous prime;
ibdv;
immune response;
prime boost ... See more keywords
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Published in 2019 at "Vaccine"
DOI: 10.1016/j.vaccine.2019.03.071
Abstract: BACKGROUND Influenza A/H7N9 viruses are undergoing antigenic drift since their emergence in 2013, and vaccination strategies are needed for pandemic preparedness. Two doses of adjuvanted monovalent inactivated influenza A/H7N9 vaccine (IIV1 A/H7N9) are needed for…
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Keywords:
h7n9;
iiv1 h7n9;
influenza h7n9;
prime boost ... See more keywords
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Published in 2017 at "Veterinary immunology and immunopathology"
DOI: 10.1016/j.vetimm.2016.11.002
Abstract: Porcine reproductive and respiratory syndrome virus (PRRSV) infection is one of the most important swine pathogens, and causes a major economic impact worldwide. Recently, a new variant type 2 PRRSV, highly pathogenic PRRSV (HP-PRRSV) has…
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Keywords:
dna;
prime boost;
prrsv infection;
vaccine ... See more keywords
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Published in 2019 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.9b01523
Abstract: New cancer vaccine strategies are required to vanquish the self-tolerance and elicit robust immune responses against tumor-associated antigens and/or neoantigens. Contemporary approaches in nanomedicine center on the use of a single nanocarrier modified with multiple…
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Keywords:
response;
prime boost;
based cancer;
cancer vaccine ... See more keywords
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Published in 2019 at "NPJ Vaccines"
DOI: 10.1038/s41541-019-0114-8
Abstract: Highly pathogenic avian influenza (HPAI) A(H5Nx) viruses continue to pose a pandemic threat. US national vaccine stockpiles are a cornerstone of the influenza pandemic preparedness plans. However, continual genetic and antigenic divergence of A(H5Nx) viruses…
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Keywords:
prime boost;
boost;
antibody;
clade ... See more keywords
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Published in 2020 at "NPJ Vaccines"
DOI: 10.1038/s41541-020-0195-4
Abstract: Cold-chain requirements affect worldwide distribution of many vaccines. In addition, vaccines requiring multiple doses impose logistical and financial burdens, as well as patient compliance barriers. To address such limitations, we have developed new technologies to…
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Keywords:
atomic layer;
layer deposition;
antigen;
prime boost ... See more keywords
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Published in 2020 at "Nature Reviews Drug Discovery"
DOI: 10.1038/s41573-020-0074-8
Abstract: Mobilizing antitumour immunity through vaccination potentially constitutes a powerful anticancer strategy but has not yet provided robust clinical benefits in large patient populations. Although major hurdles still exist, we believe that currently available strategies for…
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Keywords:
prime boost;
approach;
vaccination;
cell ... See more keywords
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Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-94364-5
Abstract: We have developed a COVID-19 vaccine, hAd5 S-Fusion + N-ETSD, that expresses SARS-CoV-2 spike (S) and nucleocapsid (N) proteins with modifications to increase immune responses delivered using a human adenovirus serotype 5 (hAd5) platform. Here, we demonstrate…
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Keywords:
subcutaneous prime;
prime boost;
covid vaccine;
vaccination ... See more keywords
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Published in 2017 at "Journal of Virology"
DOI: 10.1128/jvi.02052-16
Abstract: ABSTRACT Current seasonal influenza vaccines are efficacious when vaccine strains are matched with circulating strains. However, they do not protect antigenic variants and newly emerging pandemic and outbreak strains. Thus, there is a critical need…
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Keywords:
prime boost;
influenza;
group;
vaccine ... See more keywords