Antigen-Primed CD8+ T Cells Call DCs for Back Up.
Sign Up to like & getrecommendations! Published in 2017 at "Immunity"
DOI: 10.1016/j.immuni.2017.02.002
Abstract: Encounters between naive T lymphocytes and dendritic cells (DCs) bearing adequate co-stimulatory signals are rare. In this issue of Immunity, Brewitz et al. (2017) show that chemokines secreted by CD8+ T cells recruit myeloid and plasmacytoid DCs… read more here.
Keywords: cells call; primed cd8; cd8 cells; dcs back ... See more keywords
Culling of APCs by inflammatory cell death pathways restricts TIM3 and PD-1 expression and promotes the survival of primed CD8 T cells
Sign Up to like & getrecommendations! Published in 2017 at "Cell Death and Differentiation"
DOI: 10.1038/cdd.2017.112
Abstract: We evaluated the impact of premature cell death of antigen-presenting cells (APCs) by Caspase-1- and RipK3-signaling pathways on CD8+ T-cell priming during infection of mice with Salmonella typhimurium (ST). Our results indicate that Caspase1 and… read more here.
Keywords: ripk3; cd8 cells; primed cd8; cell death ... See more keywords
Abnormally primed CD8 T cells: The Achilles’ heel of CHB
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1106700
Abstract: Chronic hepatitis B virus (HBV) infection continues to be a significant public health challenge, and more than 250 million people around world are infected with HBV. The clearance of HBV with virus-specific CD8 T cells… read more here.
Keywords: abnormally primed; hbv; primed cd8; specific cd8 ... See more keywords