Articles with "primed pcr" as a keyword



Pulse-Field capillary electrophoresis of repeat-primed PCR amplicons for analysis of large repeats in Spinocerebellar Ataxia Type 10

Sign Up to like & get
recommendations!
Published in 2020 at "PLoS ONE"

DOI: 10.1371/journal.pone.0228789

Abstract: Large expansions of microsatellite DNA cause several neurological diseases. In Spinocerebellar ataxia type 10 (SCA10), the repeat interruptions change disease phenotype; an (ATTCC)n or a (ATCCT)n/(ATCCC)n interruption within the (ATTCT)n repeat is associated with the… read more here.

Keywords: ataxia type; spinocerebellar ataxia; repeat primed; repeat ... See more keywords
Photo from wikipedia

Accuracy and Performance Evaluation of Triplet Repeat Primed PCR as an Alternative to Conventional Diagnostic Methods for Fragile X Syndrome

Sign Up to like & get
recommendations!
Published in 2021 at "Annals of Laboratory Medicine"

DOI: 10.3343/alm.2021.41.4.394

Abstract: Background Conventional diagnosis of fragile X syndrome (FXS) is based on a combination of fragment analysis (FA) and Southern blotting (SB); however, this diagnostic approach is time- and labor-intensive and has pitfalls such as the… read more here.

Keywords: triplet repeat; conventional diagnostic; fragile syndrome; repeat primed ... See more keywords