Null alleles and sequence variations at primer binding sites of STR loci within multiplex typing systems.
Sign Up to like & getrecommendations! Published in 2018 at "Legal medicine"
DOI: 10.1016/j.legalmed.2017.10.007
Abstract: Rare variants are widely observed in human genome and sequence variations at primer binding sites might impair the process of PCR amplification resulting in dropouts of alleles, named as null alleles. In this study, 5… read more here.
Keywords: typing systems; null alleles; primer binding; sequence variations ... See more keywords
Oligo Design with Single Primer Binding Site for High Capacity DNA-Based Data Storage
Sign Up to like & getrecommendations! Published in 2020 at "IEEE/ACM Transactions on Computational Biology and Bioinformatics"
DOI: 10.1109/tcbb.2019.2940177
Abstract: DNA has become an attractive medium for long-term data archiving due to its extremely high storage density and longevity. Short single-stranded DNAs, called oligonucleotides (oligos), have been designed and synthesized to store digital data. Previous… read more here.
Keywords: dna; primer binding; dna based; storage ... See more keywords