High-fat diet intensifies MLL-AF9-induced acute myeloid leukemia through activation of the FLT3 signaling in mouse primitive hematopoietic cells
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DOI: 10.1038/s41598-020-73020-4
Abstract: Using a MLL-AF9 knock-in mouse model, we discovered that consumption of a high-fat diet (HFD) accelerates the risk of developing acute myeloid leukemia (AML). This regimen increases the clusterization of FLT3 within lipid rafts on… read more here.
Keywords: fat diet; primitive hematopoietic; high fat; mll af9 ... See more keywords