In vitro growth and maturation of primordial follicles and immature oocytes.
Sign Up to like & getrecommendations! Published in 2021 at "Fertility and sterility"
DOI: 10.1016/j.fertnstert.2021.03.004
Abstract: Cryopreservation of ovarian tissue to preserve the fertility of girls and young women at high risk of sterility is now widely practiced. Pieces of cryopreserved ovarian cortex can be thawed and autografted to restore fertility,… read more here.
Keywords: primordial follicles; ovarian tissue; vitro growth; immature oocytes ... See more keywords
High steroid content in conditioned medium of granulosa cells may disrupt primordial follicles formation in in vitro cultured one-day-old murine ovaries.
Sign Up to like & getrecommendations! Published in 2022 at "Reproductive biology"
DOI: 10.1016/j.repbio.2022.100613
Abstract: This study was conducted to investigate the main and interactive effects of two methods of culture medium preparation [base medium vs granulosa cells conditioned medium (GCCM)] and two nutrient supplements [fetal bovine serum (FBS) vs… read more here.
Keywords: expression; culture; gccm; primordial follicles ... See more keywords
BRCA-1 Gene Expression and Comparative Proteomic Profile of Primordial Follicles from Young and Adult Buffalo (Bubalus bubalis) Ovaries
Sign Up to like & getrecommendations! Published in 2017 at "Animal Biotechnology"
DOI: 10.1080/10495398.2016.1210613
Abstract: ABSTRACT In our previous study, we demonstrated that the repair efficiency of DNA double-strand breaks declines with increasing age in rat primordial follicles. In the present study, we extended our studies to buffalo (Bubalus bubalis)… read more here.
Keywords: adult buffalo; primordial follicles; buffalo bubalus; bubalus bubalis ... See more keywords
Mechanical stress accompanied with nuclear rotation is involved in the dormant state of mouse oocytes
Sign Up to like & getrecommendations! Published in 2019 at "Science Advances"
DOI: 10.1126/sciadv.aav9960
Abstract: Compression keeps oocytes dormant. The most immature oocytes remain dormant in primordial follicles in the ovary, ensuring the longevity of female reproductive life. Despite its biological and clinical importance, knowledge of mechanisms regulating the dormant… read more here.
Keywords: state; mechanical stress; primordial follicles; dormant state ... See more keywords
Comparison of methods for quantifying primordial follicles in the mouse ovary
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Ovarian Research"
DOI: 10.1186/s13048-020-00724-6
Abstract: Background Accurate evaluation of primordial follicle numbers in mouse ovaries is an essential endpoint for studies investigating how endogenous and exogenous insults, such as maternal aging and chemotherapy, impact the ovarian reserve. In this study,… read more here.
Keywords: primordial follicles; direct count; follicle; method ... See more keywords
Anethole reduces oxidative stress and improves in vitro survival and activation of primordial follicles
Sign Up to like & getrecommendations! Published in 2018 at "Brazilian Journal of Medical and Biological Research"
DOI: 10.1590/1414-431x20187129
Abstract: Primordial follicles, the main source of oocytes in the ovary, are essential for the maintenance of fertility throughout the reproductive lifespan. To the best of our knowledge, there are no reports describing the effect of… read more here.
Keywords: anethole reduces; primordial follicles; treatment; reduces oxidative ... See more keywords
Blocking the PI3K pathway or the presence of high concentrations of EGF inhibits the spontaneous activation of ovine primordial follicles in vitro
Sign Up to like & getrecommendations! Published in 2017 at "Animal reproduction"
DOI: 10.21451/1984-3143-ar925
Abstract: The aims of this study were to verify the effects of Epidermal Growth Factor (EGF) on the morphology, primordial follicle activation, growth and proliferation of granulosa cells of ovine follicles cultured in situ, as well… read more here.
Keywords: pi3k; primordial follicles; control; activation ... See more keywords
Mechanisms of primordial follicle activation and new pregnancy opportunity for premature ovarian failure patients
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2023.1113684
Abstract: Primordial follicles are the starting point of follicular development and the basic functional unit of female reproduction. Primordial follicles are formed around birth, and most of the primordial follicles then enter a dormant state. Since… read more here.
Keywords: primordial follicles; mechanisms primordial; follicle activation; activation ... See more keywords