SET domain‐containing protein 5 is required for expression of primordial germ cell specification‐associated genes in murine embryonic stem cells
Sign Up to like & getrecommendations! Published in 2017 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3269
Abstract: Primordial germ cell (PGC) specification is one of the most fundamental processes in developmental biology. Because PGCs are a common source of both gametes, generation of PGCs from embryonic stem cells (ESCs) is a useful… read more here.
Keywords: protein; primordial germ; associated genes; germ cell ... See more keywords
Biology of primordial germ cells in vertebrates with emphasis in urodeles amphibians.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular reproduction and development"
DOI: 10.1002/mrd.23533
Abstract: Primordial germ cells (PGCs) are highly specialized cells that play a relevant role in the maintenance and evolution of the species, since they create new combinations of genetic information between the organisms. Amphibians are a… read more here.
Keywords: primordial germ; urodeles amphibians; biology primordial; germ cells ... See more keywords
Transcriptional dynamics of the circulating chicken primordial germ cells revealing key genes in cell adhesion and proliferation prior to gonad colonization
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23558
Abstract: Primordial germ cells (PGCs), precursors to sperms and oocytes, are responsible for the transfer of genetic information to the next generation. The PGCs arise far away from the developing gonad and thus have to migrate… read more here.
Keywords: colonization; cell adhesion; pgcs; germ cells ... See more keywords
Presence of the matrix metalloproteinases during the migration of the primordial germ cells in zebrafish gonadal ridge.
Sign Up to like & getrecommendations! Published in 2020 at "Cell and tissue research"
DOI: 10.1007/s00441-020-03288-5
Abstract: In vertebrates, the primordial germ cells (PGCs) differentiate from extragonadal regions, migrating to gonadal ridge during the embryonic development. However, recent studies in mammals indicate that the PGCs originate from the epiblast and subsequently migrate… read more here.
Keywords: primordial germ; gonadal ridge; germ cells; migration ... See more keywords
Developmental stages, incubation temperature, and in vivo traceability of primordial germ cell in an important aquaculture species Piaractus mesopotamicus
Sign Up to like & getrecommendations! Published in 2021 at "Aquaculture"
DOI: 10.1016/j.aquaculture.2021.736381
Abstract: Abstract This study aims to describe the early development of Piaractus mesopotamicus in detail at 22 °C, 26 °C, and 30 °C and describe primordial germ cell migration in vivo by using artificial GFP-nos1 3’UTR mRNA for future… read more here.
Keywords: primordial germ; piaractus mesopotamicus; temperature; germ cell ... See more keywords
Derivation of Intermediate Pluripotent Stem Cells Amenable to Primordial Germ Cell Specification.
Sign Up to like & getrecommendations! Published in 2020 at "Cell stem cell"
DOI: 10.1016/j.stem.2020.11.003
Abstract: Dynamic pluripotent stem cell (PSC) states are in vitro adaptations of pluripotency continuum in vivo. Previous studies have generated a number of PSCs with distinct properties. To date, however, no known PSCs have demonstrated dual competency for… read more here.
Keywords: primordial germ; pluripotency; pluripotent stem; stem ... See more keywords
Expanding homogeneous culture of human primordial germ cell-like cells maintaining germline features without serum or feeder layers.
Sign Up to like & getrecommendations! Published in 2022 at "Stem cell reports"
DOI: 10.1016/j.stemcr.2022.01.012
Abstract: In vitro expansion of human primordial germ cell-like cells (hPGCLCs), a pluripotent stem cell-derived PGC model, has proved challenging due to rapid loss of primordial germ cell (PGC)-like identity and limited cell survival/proliferation. Here, we describe… read more here.
Keywords: germ cell; hpgclcs; like cells; primordial germ ... See more keywords
Early development of primordial germ cells in Pacific bluefin tuna Thunnus orientalis.
Sign Up to like & getrecommendations! Published in 2019 at "Theriogenology"
DOI: 10.1016/j.theriogenology.2019.03.031
Abstract: Bluefin tuna is one of the most important aquaculture species in several countries; however, information regarding the primordial germ cell (PGC) development and migration in this species is scarce. This information is vital for application… read more here.
Keywords: primordial germ; bluefin tuna; development; pgcs ... See more keywords
PRDM14 and BLIMP1 control the development of chicken primordial germ cells.
Sign Up to like & getrecommendations! Published in 2019 at "Developmental biology"
DOI: 10.1016/j.ydbio.2019.06.018
Abstract: The differentiation of primordial germ cells (PGCs) is a fundamental step in development. PR domain-containing protein 14 (PRDM14) and B lymphocyte-induced maturation protein 1 (BLIMP1) play pivotal roles in mouse PGC specification. In the present… read more here.
Keywords: prdm14 blimp1; primordial germ; germ cells; prdm14 ... See more keywords
MASTL is essential for anaphase entry of proliferating primordial germ cells and establishment of female germ cells in mice
Sign Up to like & getrecommendations! Published in 2017 at "Cell Discovery"
DOI: 10.1038/celldisc.2016.52
Abstract: In mammals, primordial germ cells (PGCs) are the embryonic cell population that serve as germ cell precursors in both females and males. During mouse embryonic development, the majority of PGCs are arrested at the G2… read more here.
Keywords: primordial germ; germ cells; germ; anaphase entry ... See more keywords
Differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-07740-7
Abstract: A major challenge in stem cell differentiation is the availability of bioassays to prove cell types generated in vitro are equivalent to cells in vivo. In the mouse, differentiation of primordial germ cell-like cells (PGCLCs)… read more here.
Keywords: primordial germ; like cells; differentiation; germ cell ... See more keywords