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Published in 2017 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3269
Abstract: Primordial germ cell (PGC) specification is one of the most fundamental processes in developmental biology. Because PGCs are a common source of both gametes, generation of PGCs from embryonic stem cells (ESCs) is a useful…
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Keywords:
protein;
primordial germ;
associated genes;
germ cell ... See more keywords
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Published in 2021 at "Molecular reproduction and development"
DOI: 10.1002/mrd.23533
Abstract: Primordial germ cells (PGCs) are highly specialized cells that play a relevant role in the maintenance and evolution of the species, since they create new combinations of genetic information between the organisms. Amphibians are a…
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Keywords:
primordial germ;
urodeles amphibians;
biology primordial;
germ cells ... See more keywords
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Published in 2022 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23558
Abstract: Primordial germ cells (PGCs), precursors to sperms and oocytes, are responsible for the transfer of genetic information to the next generation. The PGCs arise far away from the developing gonad and thus have to migrate…
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Keywords:
colonization;
cell adhesion;
pgcs;
germ cells ... See more keywords
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Published in 2020 at "Cell and tissue research"
DOI: 10.1007/s00441-020-03288-5
Abstract: In vertebrates, the primordial germ cells (PGCs) differentiate from extragonadal regions, migrating to gonadal ridge during the embryonic development. However, recent studies in mammals indicate that the PGCs originate from the epiblast and subsequently migrate…
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Keywords:
primordial germ;
gonadal ridge;
germ cells;
migration ... See more keywords
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Published in 2021 at "Aquaculture"
DOI: 10.1016/j.aquaculture.2021.736381
Abstract: Abstract This study aims to describe the early development of Piaractus mesopotamicus in detail at 22 °C, 26 °C, and 30 °C and describe primordial germ cell migration in vivo by using artificial GFP-nos1 3’UTR mRNA for future…
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Keywords:
primordial germ;
piaractus mesopotamicus;
temperature;
germ cell ... See more keywords
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Published in 2020 at "Cell stem cell"
DOI: 10.1016/j.stem.2020.11.003
Abstract: Dynamic pluripotent stem cell (PSC) states are in vitro adaptations of pluripotency continuum in vivo. Previous studies have generated a number of PSCs with distinct properties. To date, however, no known PSCs have demonstrated dual competency for…
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Keywords:
primordial germ;
pluripotency;
pluripotent stem;
stem ... See more keywords
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Published in 2022 at "Stem cell reports"
DOI: 10.1016/j.stemcr.2022.01.012
Abstract: In vitro expansion of human primordial germ cell-like cells (hPGCLCs), a pluripotent stem cell-derived PGC model, has proved challenging due to rapid loss of primordial germ cell (PGC)-like identity and limited cell survival/proliferation. Here, we describe…
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Keywords:
germ cell;
hpgclcs;
like cells;
primordial germ ... See more keywords
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Published in 2019 at "Theriogenology"
DOI: 10.1016/j.theriogenology.2019.03.031
Abstract: Bluefin tuna is one of the most important aquaculture species in several countries; however, information regarding the primordial germ cell (PGC) development and migration in this species is scarce. This information is vital for application…
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Keywords:
primordial germ;
bluefin tuna;
development;
pgcs ... See more keywords
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Published in 2019 at "Developmental biology"
DOI: 10.1016/j.ydbio.2019.06.018
Abstract: The differentiation of primordial germ cells (PGCs) is a fundamental step in development. PR domain-containing protein 14 (PRDM14) and B lymphocyte-induced maturation protein 1 (BLIMP1) play pivotal roles in mouse PGC specification. In the present…
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Keywords:
prdm14 blimp1;
primordial germ;
germ cells;
prdm14 ... See more keywords
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Published in 2017 at "Cell Discovery"
DOI: 10.1038/celldisc.2016.52
Abstract: In mammals, primordial germ cells (PGCs) are the embryonic cell population that serve as germ cell precursors in both females and males. During mouse embryonic development, the majority of PGCs are arrested at the G2…
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Keywords:
primordial germ;
germ cells;
germ;
anaphase entry ... See more keywords
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Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-07740-7
Abstract: A major challenge in stem cell differentiation is the availability of bioassays to prove cell types generated in vitro are equivalent to cells in vivo. In the mouse, differentiation of primordial germ cell-like cells (PGCLCs)…
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Keywords:
primordial germ;
like cells;
differentiation;
germ cell ... See more keywords