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Published in 2020 at "Current opinion in biotechnology"
DOI: 10.1016/j.copbio.2019.12.012
Abstract: Bacteria are widely used for commercially producing biomolecules. However, attempts to rationally design production strains and optimize cultivation conditions are frequently counteracted by the emergence of mutants with reduced production characteristics that decrease overall process…
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Keywords:
ecological evolutionary;
evolutionary principles;
production;
principles guide ... See more keywords
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Published in 2017 at "Annals of Surgery"
DOI: 10.1097/sla.0000000000001962
Abstract: Objective: To identify the core principles that guide expert intraoperative behaviors and to use these principles to develop a universal framework that defines intraoperative performance. Background: Surgical outcomes are associated with intraoperative cognitive skills. Yet,…
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Keywords:
behaviors operating;
framework;
principles guide;
guide behaviors ... See more keywords
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Published in 2017 at "Annals of the American Thoracic Society"
DOI: 10.1513/annalsats.201607-569ps
Abstract: Americans face inevitable trade-offs between health care affordability, accessibility, and innovation. Although numerous reforms have been proposed, universal principles to guide decision-making are lacking. Solving the challenges that confront us will be difficult, owing to…
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Keywords:
health care;
principles guide;
high value;
health ... See more keywords