Principles of Ubiquitin-Dependent Signaling.
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DOI: 10.1146/annurev-cellbio-100617-062802
Abstract: Ubiquitylation is an essential posttranslational modification that controls cell division, differentiation, and survival in all eukaryotes. By combining multiple E3 ligases (writers), ubiquitin-binding effectors (readers), and de-ubiquitylases (erasers) with functionally distinct ubiquitylation tags, the ubiquitin… read more here.
Keywords: ubiquitin dependent; principles ubiquitin; dependent signaling; biology ... See more keywords