Alkynyl Prins carbocyclization cascades for the synthesis of linear-fused heterocyclic ring systems
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DOI: 10.1039/d2sc04750k
Abstract: We report a Brønsted acid-catalyzed carbocyclization cascade, featuring condensation of an alcohol/sulfonamide with an aldehyde followed by an intramolecular three-component coupling involving an alkyne, an oxocarbenium/iminium ion, and an arene. A formal cycloaddition is embedded… read more here.
Keywords: carbocyclization cascades; cascades synthesis; chemistry; prins carbocyclization ... See more keywords