Soluble amyloid‐β dimers are resistant to amyloid‐β prion conversion in vivo suggesting antiprion properties
Sign Up to like & getrecommendations! Published in 2023 at "Neuropathology and Applied Neurobiology"
DOI: 10.1111/nan.12895
Abstract: According to the instructions for authors, short communications should be published without abstract. read more here.
Keywords: resistant amyloid; dimers resistant; prion conversion; soluble amyloid ... See more keywords
Endogenous Brain Lipids Inhibit Prion Amyloid Formation In Vitro
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DOI: 10.1128/jvi.02162-16
Abstract: ABSTRACT The normal cellular prion protein (PrPC) resides in detergent-resistant outer membrane lipid rafts in which conversion to the pathogenic misfolded form is believed to occur. Once misfolding occurs, the pathogenic isoform polymerizes into highly… read more here.
Keywords: prion conversion; prion; conversion; brain ... See more keywords
What is the role of lipids in prion conversion and disease?
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DOI: 10.3389/fnmol.2022.1032541
Abstract: The molecular cause of transmissible spongiform encephalopathies (TSEs) involves the conversion of the cellular prion protein (PrPC) into its pathogenic form, called prion scrapie (PrPSc), which is prone to the formation of amorphous and amyloid… read more here.
Keywords: prion; prpsc; conversion; prion conversion ... See more keywords