OR1. Invisible organs made by genetic engineering to turn off MHC prior to allogeneic transplantation prevent a pro-inflammatory cytokine response in the recipient
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DOI: 10.1016/j.humimm.2018.07.006
Abstract: Aim HLA and minor antigen mismatches are the main causes of allograft rejection and graft failure. We have shown in mice and rats that MHC silenced cells and tissues are protected against immune rejection. We… read more here.
Keywords: prior allogeneic; transplantation; cytokine response; lung ... See more keywords