HDAC6 as privileged target in drug discovery: A perspective.
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DOI: 10.1016/j.phrs.2020.105274
Abstract: HDAC6, a class II b HDAC isoenzyme, stands unique in its structural and physiological functions. Besides histone modification, largely due to its cytoplasmic localization, HDAC6 also targets several non-histone proteins including Hsp90, α-tubulin, cortactin, HSF1,… read more here.
Keywords: privileged target; discovery perspective; target drug; hdac6 ... See more keywords