Articles with "prkcsh contributes" as a keyword



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PRKCSH contributes to tumorigenesis by selective boosting of IRE1 signaling pathway

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Published in 2019 at "Nature Communications"

DOI: 10.1038/s41467-019-11019-w

Abstract: Unfolded protein response (UPR) is an adaptive mechanism that aims at restoring ER homeostasis under severe environmental stress. Malignant cells are resistant to environmental stress, which is largely due to an activated UPR. However, the… read more here.

Keywords: ire1; environmental stress; stress; prkcsh contributes ... See more keywords