Resistant peanut cultivars reduce peanut root‐knot nematode infestation in field production
Sign Up to like & getrecommendations! Published in 2025 at "Agronomy Journal"
DOI: 10.1002/agj2.70249
Abstract: Meloidogyne arenaria (peanut root‐knot nematode [PRKN]) is the most important plant–parasitic nematode on peanut ( Arachis hypogea ) in the United States. Some PRKN‐resistant cultivars are available, but comparisons among these cultivars in the field… read more here.
Keywords: field; georgia; peanut root; prkn ... See more keywords
Parkin is Transcriptionally Regulated by the Aryl Hydrocarbon Receptor: Impact on α-Synuclein Protein Levels.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2019.08.002
Abstract: Parkin (PRKN) is a ubiquitin E3 ligase that catalyzes the ubiquitination of several proteins. Mutations in the human Parkin gene, PRKN, leads to degeneration of dopaminergic (DA) neurons, resulting in autosomal recessive early-onset parkinsonism and… read more here.
Keywords: aryl hydrocarbon; hydrocarbon receptor; prkn; protein levels ... See more keywords
PTEN-L puts a brake on mitophagy
Sign Up to like & getrecommendations! Published in 2018 at "Autophagy"
DOI: 10.1080/15548627.2018.1502565
Abstract: ABSTRACT Mitophagy is a main type of selective autophagy, via which damaged mitochondria are selectively degraded via the autophagic pathway. The protein kinase PINK1 and E3 ubiquitin ligase PRKN are the most well studied regulators… read more here.
Keywords: protein; pten puts; brake mitophagy; prkn ... See more keywords
Loss of MIEF1/MiD51 confers susceptibility to BAX-mediated cell death and PINK1-PRKN-dependent mitophagy
Sign Up to like & getrecommendations! Published in 2019 at "Autophagy"
DOI: 10.1080/15548627.2019.1596494
Abstract: ABSTRACT Mitochondrial dynamics is highly implicated in a plethora of cellular processes including apoptosis and mitophagy. However, little is known about the scope and precise functions of mitochondrial dynamics proteins for mitochondrial quality control and… read more here.
Keywords: protein; mief1 mid51; prkn; mief1 ... See more keywords
HIV-1 Nef counteracts autophagy restriction by enhancing the association between BECN1 and its inhibitor BCL2 in a PRKN-dependent manner
Sign Up to like & getrecommendations! Published in 2020 at "Autophagy"
DOI: 10.1080/15548627.2020.1725401
Abstract: ABSTRACT Macroautophagy/autophagy is an auto-digestive pro-survival pathway activated in response to stress to target cargo for lysosomal degradation. In recent years, autophagy has become prominent as an innate antiviral defense mechanism through multiple processes, such… read more here.
Keywords: restriction; hiv; enhancing association; prkn ... See more keywords
Regulation of PRKN-Independent Mitophagy.
Sign Up to like & getrecommendations! Published in 2021 at "Autophagy"
DOI: 10.1080/15548627.2021.1888244
Abstract: Mitochondria are dynamic, multifunctional cellular organelles that play a fundamental role in maintaining cellular homeostasis. Keeping the quality of mitochondria in check is of essential importance for functioning and survival of the cells. Selective autophagic… read more here.
Keywords: regulation prkn; independent mitophagy; prkn independent; prkn ... See more keywords
Feedforward activation of PRKN/parkin
Sign Up to like & getrecommendations! Published in 2022 at "Autophagy"
DOI: 10.1080/15548627.2022.2100615
Abstract: ABSTRACT Parkinson disease is a neurodegenerative disorder characterized by the progressive loss of dopaminergic neurons in the midbrain. The majority of early onset forms of Parkinson disease are a result of autosomal mutations in PRKN… read more here.
Keywords: activation prkn; parkinson disease; feedforward activation; prkn ... See more keywords
Activation of BK channels prevents diabetes-induced osteopenia by regulating mitochondrial Ca2+ and SLC25A5/ANT2-PINK1-PRKN-mediated mitophagy
Sign Up to like & getrecommendations! Published in 2024 at "Autophagy"
DOI: 10.1080/15548627.2024.2367184
Abstract: ABSTRACT Osteopenia and osteoporosis are among the most common metabolic bone diseases and represent major public health problems, with sufferers having an increased fracture risk. Diabetes is one of the most common diseases contributing to… read more here.
Keywords: slc25a5 ant2; diabetes induced; ca2; prkn ... See more keywords
Novel Compound Heterozygous PRKN Variants in a Han-Chinese Family with Early-Onset Parkinson's Disease
Sign Up to like & getrecommendations! Published in 2019 at "Parkinson's Disease"
DOI: 10.1155/2019/9024894
Abstract: Genetic factors are thought to play an important role in the pathogenesis of Parkinson's disease (PD), particularly early-onset PD. The PRKN gene is the primary disease-causing gene for early-onset PD. The details of its functions… read more here.
Keywords: early onset; disease; novel compound; prkn ... See more keywords
Pediatric-onset PRKN disease: New insights into an understudied population
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Parkinson's Disease"
DOI: 10.1177/1877718x241296153
Abstract: Background In pediatric age, the PRKN mutation is reported as one of the most common genetic causes of Parkinson's disease. However, detailed clinical data on PRKN patients with pediatric onset are scarce. Objective To describe… read more here.
Keywords: age; pediatric onset; disease; diagnosis ... See more keywords
Fluopyram or Resistant Cultivars Manage Meloidogyne arenaria Infestation in Virginia-Type Peanut Production
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Nematology"
DOI: 10.2478/jofnem-2025-0010
Abstract: Abstract Meloidogyne arenaria (peanut root-knot nematode, PRKN) is an important pest in peanut (Arachis hypogea) production in the United States, including specialty Virginia-type peanuts. Cultivars resistant to PRKN and nematicide application are two available methods… read more here.
Keywords: peanut; fluopyram; virginia type; prkn ... See more keywords