Association of prolactin receptor (PRLR) variants with prolactinomas
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DOI: 10.1093/hmg/ddy396
Abstract: Abstract Prolactinomas are the most frequent type of pituitary tumors, which represent 10–20% of all intracranial neoplasms in humans. Prolactinomas develop in mice lacking the prolactin receptor (PRLR), which is a member of the cytokine… read more here.
Keywords: receptor prlr; prlr; prolactin receptor; prlr variants ... See more keywords
Identification of prolactin receptor variants with diverse effects on receptor signalling
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Molecular Endocrinology"
DOI: 10.1530/jme-22-0164
Abstract: The prolactin receptor (PRLR) signals predominantly through the JAK2-STAT5 pathway regulating multiple physiological functions relating to fertility, lactation, and metabolism. However, the molecular pathology and role of PRLR mutations and signalling are incompletely defined, with… read more here.
Keywords: prlr; prolactin receptor; prlr variants; receptor ... See more keywords