prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis.
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DOI: 10.1073/pnas.2218899120
Abstract: Cleavage of the flavivirus premembrane (prM) structural protein during maturation can be inefficient. The contribution of partially mature flavivirus virions that retain uncleaved prM to pathogenesis during primary infection is unknown. To investigate this question,… read more here.
Keywords: prm; partially mature; prm reactive; pathogenesis ... See more keywords