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PRMT8 Attenuates Cerebral Ischemia/Reperfusion Injury via Modulating Microglia Activation and Polarization to Suppress Neuroinflammation by Upregulating Lin28a.

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Published in 2022 at "ACS chemical neuroscience"

DOI: 10.1021/acschemneuro.2c00096

Abstract: Activation and polarization of microglia are involved in neuroinflammation and regulate ischemic stroke-associated brain injury. Protein arginine methyltransferase 8 functions as a regulatory component of hypoxic stress-induced neuroinflammation. The protective effect of protein arginine methyltransferase… read more here.

Keywords: prmt8; neuroinflammation; activation polarization; polarization ... See more keywords