Elucidating the role of PRMTs in prostate cancer using open access databases and a patient cohort dataset.
Sign Up to like & getrecommendations! Published in 2022 at "Histology and histopathology"
DOI: 10.14670/hh-18-513
Abstract: Protein arginine methylation is an understudied epigenetic mechanism catalyzed by enzymes known as Protein Methyltransferases of Arginine (PRMTs), while the opposite reaction is performed by Jumonji domain- containing protein 6 (JMJD6). There is increasing evidence… read more here.
Keywords: prostate cancer; jmjd6; prmts; expression ... See more keywords
Type I and II PRMTs inversely regulate post-transcriptional intron detention through Sm and CHTOP methylation
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DOI: 10.7554/elife.72867
Abstract: Protein arginine methyltransferases (PRMTs) are required for the regulation of RNA processing factors. Type I PRMT enzymes catalyze mono- and asymmetric dimethylation; Type II enzymes catalyze mono- and symmetric dimethylation. To understand the specific mechanisms… read more here.
Keywords: prmts; regulate post; type prmts; chtop ... See more keywords