Treat and extend versus pro re nata regimens of ranibizumab and aflibercept in neovascular age-related macular degeneration: a comparative study
Sign Up to like & getrecommendations! Published in 2019 at "Graefe's Archive for Clinical and Experimental Ophthalmology"
DOI: 10.1007/s00417-019-04404-0
Abstract: To compare treatment efficacy of anti-VEGF medications following pro re nata (PRN, “as needed”, monthly injections only in case of active disease) or treat and extend (T&E, progressive extension of treatment intervals up to 12… read more here.
Keywords: treatment; group; ranibizumab aflibercept; prn ... See more keywords
Enhanced Efficacy of Propranolol Therapy for Infantile Hemangiomas based on a Mesoporous Silica Nanoplatform through Mediating Autophagy Dysfunction.
Sign Up to like & getrecommendations! Published in 2020 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2020.02.033
Abstract: Infantile hemangioma is one of the most common vascular tumors, which might result in morbidity and mortality without timely intervention. Propranolol is currently the first-line therapy for hemangiomas, but its potential side effects and high… read more here.
Keywords: prn msn; autophagy dysfunction; mesoporous silica; propranolol ... See more keywords
Development of a pertactin coated beads approach for screening of functional monoclonal antibodies.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2019.10.001
Abstract: Vaccine manufacturers have recently focused on the development of in vitro potency assays to promote 3R's strategy to replace animal testing. To be able to develop an in vitro potency assay, the immunological characteristics of… read more here.
Keywords: monoclonal antibodies; coated beads; screening functional; approach ... See more keywords
Reducing Therapeutic Duplication in Inpatient Medication Orders
Sign Up to like & getrecommendations! Published in 2023 at "Applied clinical informatics"
DOI: 10.1055/a-2082-4631
Abstract: BACKGROUND Therapeutic duplication, the presence of multiple agents prescribed for the same indication without clarification for when each should be used, can contribute to serious medical errors. Joint Commission standards require that orders contain clarifying… read more here.
Keywords: acetaminophen ibuprofen; therapeutic duplication; reducing therapeutic; line ... See more keywords
Injektionsstrategien bei der Anwendung intravitrealer VEGF-Inhibitoren: „Pro Re Nata versus Treat and Extend“
Sign Up to like & getrecommendations! Published in 2017 at "Klinische Monatsblatter Fur Augenheilkunde"
DOI: 10.1055/s-0042-122340
Abstract: Das Ziel dieses Artikels ist es, einen Uberblick zu geben uber verschiedene Strategien zur Verwendung von PRN- und TE T&E: treat and extend) mit intravitrealen Anti-VEGF-Medikamenten (Bevacizumab, Ranibizumab oder Aflibercept) bei Patienten mit Netzhauterkrankungen wie… read more here.
Keywords: bei; der; treat extend; prn ... See more keywords
Characterization of Psychotropic PRN Medications in a Canadian Psychiatric Intensive Care Unit.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the American Psychiatric Nurses Association"
DOI: 10.1177/1078390321994668
Abstract: OBJECTIVE Pro re nata (PRN) antipsychotics and benzodiazepines are routinely used for the rapid stabilization of acutely agitated patients. Despite the popular use of PRN medications in mental health units, primary literature supporting efficacy and… read more here.
Keywords: prn; care unit; psychiatric intensive; intensive care ... See more keywords
Prescription patterns in psychiatric compulsory care: polypharmacy and high-dose antipsychotics
Sign Up to like & getrecommendations! Published in 2021 at "BJPsych Open"
DOI: 10.1192/bjo.2021.982
Abstract: Background Antipsychotic polypharmacy and prescription of high-dose antipsychotics are often used for the treatment of psychotic symptoms, especially in compulsory psychiatric care although there is lack of evidence to support this practice and related risks… read more here.
Keywords: high dose; prescription; polypharmacy; prn ... See more keywords
Effect of FHA and Prn on Bordetella pertussis colonization of mice is dependent on vaccine type and anatomical site
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0237394
Abstract: Bordetella pertussis vaccine escape mutants that lack expression of the pertussis antigen pertactin (Prn) have emerged in vaccinated populations in the last 10–20 years. Additionally, clinical isolates lacking another acellular pertussis (aP) vaccine component, filamentous… read more here.
Keywords: fha; vaccine; bordetella pertussis; anatomical site ... See more keywords
Polyhydroxyalkanoate (PHA) Polymer Accumulation and pha Gene Expression in Phenazine (phz-) and Pyrrolnitrin (prn-) Defective Mutants of Pseudomonas chlororaphis PA23
Sign Up to like & getrecommendations! Published in 2018 at "Polymers"
DOI: 10.3390/polym10111203
Abstract: Pseudomonas chlororaphis PA23 was isolated from the rhizosphere of soybeans and identified as a biocontrol bacterium against Sclerotinia sclerotiorum, a fungal plant pathogen. This bacterium produces a number of secondary metabolites, including phenazine-1-carboxylic acid, 2-hydroxyphenazine,… read more here.
Keywords: pha; phz prn; expression; prn ... See more keywords