TGFβ+ small extracellular vesicles from head and neck squamous cell carcinoma cells reprogram macrophages towards a pro‐angiogenic phenotype
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12294
Abstract: Abstract Transforming growth factor β (TGFβ) is a major component of tumor‐derived small extracellular vesicles (TEX) in cancer patients. Mechanisms utilized by TGFβ+ TEX to promote tumor growth and pro‐tumor activities in the tumor microenvironment… read more here.
Keywords: cell; extracellular vesicles; phenotype; tgf ... See more keywords
Towards a biotechnological platform for the production of human pro-angiogenic growth factors in the green alga Chlamydomonas reinhardtii
Sign Up to like & getrecommendations! Published in 2019 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-019-10267-6
Abstract: The recent use of photosynthetic organisms such as Chlamydomonas reinhardtii in biomedical applications has demonstrated their potential for the treatment of acute and chronic tissue hypoxia. Moreover, transgenic microalgae have been suggested as an alternative… read more here.
Keywords: human pro; pro angiogenic; growth factors; angiogenic growth ... See more keywords
Early Anti-inflammatory and Pro-angiogenic Myocardial Effects of Intravenous Serelaxin Infusion for 72 H in an Experimental Rat Model of Acute Myocardial Infarction
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cardiovascular Translational Research"
DOI: 10.1007/s12265-017-9761-1
Abstract: Sprague Dawley rats were subjected to acute myocardial infarction (AMI) by permanent ligation of the left anterior descending coronary artery. At the time of AMI, a subcutaneous mini-osmotic pump was implanted and animals were randomized… read more here.
Keywords: anti inflammatory; pro angiogenic; early anti; myocardial infarction ... See more keywords
Fentanyl stimulates tumor angiogenesis via activating multiple pro-angiogenic signaling pathways.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.08.038
Abstract: Angiogenesis plays a vital role in tumor progression and metastasis. To better understand the role of anesthesia in tumor biology, we previously reported that bupivacaine displayed the inhibitory effects in endothelial cells. In this work,… read more here.
Keywords: signaling pathways; pro angiogenic; angiogenesis; multiple pro ... See more keywords
A “controlled CO release” and “pro-angiogenic gene” dually engineered stimulus-responsive nanoplatform for collaborative ischemia therapy
Sign Up to like & getrecommendations! Published in 2021 at "Chemical Engineering Journal"
DOI: 10.1016/j.cej.2021.130430
Abstract: Abstract Ischemic injury is mostly caused by insufficient blood supply, excessive inflammation and increased oxidative stress. Pro-angiogenic gene delivery can foster vascular remodeling and increase blood perfusion, but the adverse ischemia microenvironment leads to inadequate… read more here.
Keywords: ischemia therapy; therapy; pro angiogenic; angiogenic gene ... See more keywords
Redefining malignant pleural mesothelioma types as a continuum uncovers immune-vascular interactions
Sign Up to like & getrecommendations! Published in 2019 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2019.09.003
Abstract: Background Malignant Pleural Mesothelioma (MPM) is an aggressive disease related to asbestos exposure, with no effective therapeutic options. Methods We undertook unsupervised analyses of RNA-sequencing data of 284 MPMs, with no assumption of discreteness. Using… read more here.
Keywords: pro angiogenic; prognosis; pleural mesothelioma; malignant pleural ... See more keywords
Pro-Angiogenic Macrophage Phenotype to Promote Myocardial Repair.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2019.03.503
Abstract: BACKGROUND Heart failure following myocardial infarction (MI) remains one of the major causes of death worldwide, and its treatment is a crucial challenge of cardiovascular medicine. An attractive therapeutic strategy is to stimulate endogenous mechanisms… read more here.
Keywords: pro angiogenic; treatment; macrophage; mice ... See more keywords
Can adipose stromal cells replace retinal pericytes in diabetic retinopathy? In vitro comparison of pro-angiogenic capacities of human ASC and retinal pericytes
Sign Up to like & getrecommendations! Published in 2020 at "Cytotherapy"
DOI: 10.1016/j.jcyt.2020.04.058
Abstract: Background & Aim Pericyte dropout is a significant contribution to the microvascular complications leading to diabetic retinopathy (DR). The similarities with pericytes render adipose stromal cells (ASC) candidates to prevent vessel destabilization and control neoangiogenesis.… read more here.
Keywords: pro angiogenic; diabetic retinopathy; stromal cells; asc retinal ... See more keywords
Salvianolic acid B and ferulic acid synergistically promote angiogenesis in HUVECs and zebrafish via regulating VEGF signaling.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2021.114667
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Induced vascular growth in the myocardium has been widely acknowledged as a promising intervention strategy for patients with ischemic coronary artery disease. Yet despite long-term efforts on gene, protein or cell-based pro-angiogenic therapies,… read more here.
Keywords: medicine; pro angiogenic; angiogenesis; salvianolic acid ... See more keywords
In vivo pro-angiogenic effects of dracorhodin perchlorate in zebrafish embryos: A novel bioactivity evaluation platform for commercial dragon blood samples.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of food and drug analysis"
DOI: 10.1016/j.jfda.2018.08.005
Abstract: Dragon blood has been used in wound treatment for many years and can be obtained from several distinct plant species. Dracorhodin, the active substituent of dragon blood, is a characteristic compound of the palm tree,… read more here.
Keywords: commercial dragon; pro angiogenic; blood samples; dragon ... See more keywords
Chebulagic acid Chebulinic acid and Gallic acid, the active principles of Triphala, inhibit TNFα induced pro-angiogenic and pro-inflammatory activities in retinal capillary endothelial cells by inhibiting p38, ERK and NFkB phosphorylation.
Sign Up to like & getrecommendations! Published in 2018 at "Vascular pharmacology"
DOI: 10.1016/j.vph.2018.04.005
Abstract: Tumor necrosis factor-α (TNFα) a pleiotropic cytokine induces pro-inflammatory and pro-angiogenic changes in conditions such as diabetic retinopathy (DR) and neovascular age related macular degeneration (NV-AMD). Hence, inhibition of TNFα mediated changes can benefit the… read more here.
Keywords: pro angiogenic; chebulagic acid; tnf; tnf induced ... See more keywords